{ "tag": [ "compiled" ], "id": "ocds-h6vhtk-034c1a-2022-06-29T15:11:20+01:00", "date": "2022-06-29T15:11:20+01:00", "ocid": "ocds-h6vhtk-034c1a", "description": "NOTE: To register your interest in this notice and obtain any additional information please visit the Public Contracts Scotland Web Site at https://www.publiccontractsscotland.gov.uk/Search/Search_Switch.aspx?ID=698752. The buyer has indicated that it will accept electronic responses to this notice via the Postbox facility. A user guide is available at https://www.publiccontractsscotland.gov.uk/sitehelp/help_guides.aspx. Suppliers are advised to allow adequate time for uploading documents and to dispatch the electronic response well in advance of the closing time to avoid any last minute problems. (SC Ref:698752) Download the ESPD document here: https://www.publiccontractsscotland.gov.uk/ESPD/ESPD_Download.aspx?id=698752", "initiationType": "tender", "tender": { "id": "UoD-LAB424-TC-2022", "legalBasis": { "id": "32014L0024", "scheme": "CELEX" }, "title": "Supply of a Biophysical Equipment System", "status": "active", "classification": { "scheme": "CPV", "id": "38000000", "description": "Laboratory, optical and precision equipments (excl. glasses)" }, "mainProcurementCategory": "goods", "description": "Biophysical characterization of binary and ternary complex formations in proximity-inducing compounds is a key step in the iterative improvement of potency of Proteolysis Targeting Chimeras (PROTACs) and molecular glues. In order for us to have the ability to scrutinise the affinity and kinetics of binary and ternary complexes with challenging sample requirements (e.g. low affinity (1-10 uM) complexes, low protein availability, homoPROTACs etc) highly specialised systems are required. The technique will provide a readout of compound/PROTAC affinity while providing insight into additional biophysical parameters, all of which can be critical for compound optimization/prioritization. This tender aims to substantially increase the ability of biophysicists and chemists to assess PROTAC/molecular glue biophysics and will be complimentary to techniques currently available to the new Center for Targeted Protein Degradation (CeTPD) (including SPR, ITC, TR-FRET) while being able to probe interactions that other techniques cannot currently scrutinise. The new machine will be housed in the CeTPD.", "lots": [ { "id": "1", "description": "Biophysical characterization of binary and ternary complex formations in proximity-inducing compounds is a key step in the iterative improvement of potency of Proteolysis Targeting Chimeras (PROTACs) and molecular glues. In order for us to have the ability to scrutinise the affinity and kinetics of binary and ternary complexes with challenging sample requirements (e.g. low affinity (1-10 uM) complexes, low protein availability, homoPROTACs etc) highly specialised systems are required. The technique will provide a readout of compound/PROTAC affinity while providing insight into additional biophysical parameters, all of which can be critical for compound optimization/prioritization. This tender aims to substantially increase the ability of biophysicists and chemists to assess PROTAC/molecular glue biophysics and will be complimentary to techniques currently available to the new Center for Targeted Protein Degradation (CeTPD) (including SPR, ITC, TR-FRET) while being able to probe interactions that other techniques cannot currently scrutinise. The new machine will be housed in the CeTPD.", "contractPeriod": { "durationInDays": 360 }, "hasRenewal": true, "renewal": { "description": "Extended warranty/service if taken out later and not at time of equipment purchase." }, "submissionTerms": { "variantPolicy": "notAllowed" }, "hasOptions": false, "status": "active" } ], "items": [ { "id": "1", "additionalClassifications": [ { "scheme": "CPV", "id": "38000000", "description": "Laboratory, optical and precision equipments (excl. glasses)" } ], "deliveryAddresses": [ { "region": "UKM71" } ], "relatedLot": "1" } ], "submissionMethod": [ "electronicSubmission" ], "submissionMethodDetails": "http://www.publiccontractsscotland.gov.uk", "selectionCriteria": { "criteria": [ { "type": "suitability", "description": "As detailed in SPD Scotland.", "appliesTo": [ "supplier" ] } ] }, "documents": [ { "id": "economic", "documentType": "economicSelectionCriteria" }, { "id": "technical", "documentType": "technicalSelectionCriteria" } ], "contractTerms": { "performanceTerms": "As detailed in the procurement documents.", "hasElectronicOrdering": true, "electronicInvoicingPolicy": "allowed", "hasElectronicPayment": true }, "procurementMethod": "open", "procurementMethodDetails": "Open procedure", "coveredBy": [ "GPA" ], "tenderPeriod": { "endDate": "2022-07-29T12:00:00+01:00" }, "submissionTerms": { "languages": [ "en" ] }, "awardPeriod": { "startDate": "2022-07-29T12:00:00+01:00" }, "bidOpening": { "date": "2022-07-29T12:00:00+01:00" }, "hasRecurrence": false }, "parties": [ { "id": "GB-FTS-50355", "name": "University of Dundee", "identifier": { "legalName": "University of Dundee" }, "address": { "streetAddress": "4 King Edward Street", "locality": "Markinch", "region": "UKM71", "postalCode": "DD1 4HN", "countryName": "United Kingdom" }, "contactPoint": { "name": "Tracy Templeman", "telephone": "+44 1382386810", "email": "t.templeman@dundee.ac.uk", "url": "http://www.publiccontractsscotland.gov.uk" }, "roles": [ "buyer" ], "details": { "url": "http://www.dundee.ac.uk", "buyerProfile": "https://www.publiccontractsscotland.gov.uk/search/Search_AuthProfile.aspx?ID=AA00105", "classifications": [ { "scheme": "TED_CA_TYPE", "id": "BODY_PUBLIC", "description": "Body governed by public law" }, { "scheme": "COFOG", "id": "09", "description": "Education" } ] } }, { "id": "GB-FTS-50356", "name": "Dundee Sheriff Court", "identifier": { "legalName": "Dundee Sheriff Court" }, "address": { "streetAddress": "6 West Bell Street", "locality": "Dundee", "postalCode": "dd1 9ad", "countryName": "United Kingdom" }, "contactPoint": { "telephone": "+44 1382229961" }, "roles": [ "reviewBody" ] }, { "id": "GB-FTS-1026", "name": "Dundee Sheriff Court", "identifier": { "legalName": "Dundee Sheriff Court" }, "address": { "streetAddress": "6 West Bell Street", "locality": "Dundee", "postalCode": "DD1 9AD", "countryName": "United Kingdom" }, "contactPoint": { "telephone": "+44 1382229961" }, "roles": [ "mediationBody", "reviewContactPoint" ] } ], "buyer": { "id": "GB-FTS-50355", "name": "University of Dundee" }, "links": [ { "rel": "canonical", "href": "https://api.publiccontractsscotland.gov.uk/v1/Notice?id=ocds-r6ebe6-0000698752" } ], "language": "en" }