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This project funded brings together clinicians and scientists from prominent academic centres across Europe and industrial partners to conduct research into advanced liver disease/cirrhosis caused by non-alcoholic fatty liver disease (NAFLD). Their common goals are developing, validating and qualifying better biomarkers for NAFLD. Strongly associated with the epidemics of obesity and type 2 diabetes that are testing healthcare systems worldwide, NAFLD is an increasingly common cause of advanced liver disease that is characterized by substantial inter-patient variability in severity and rate of progression. Biomarkers under investigation in the project include genes that contribute to NAFLD progression. 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