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    "description": "The MRI that has been purchased for LARIF requires 2 cardiac output monitors which can be used within the MR environment. Vygon are the only supplier that uses proprietary software which can be used with the MRI system that has been purchased and installed for the facility. Cardiac output (CO) is an important and valuable physiological variable, the measurement of which can add a great deal of information to, and improve the care of, intensive care patients. Pressure recording analytical method (PRAM) is a non-invasive method of measuring cardiac output providing second-by-second information about a patient's cardiovascular status. The \"MostCare Up\" is a PRAM-CO monitor which has been used over a wide range of haemodynamic states and as proven itself comparable with the invasive \"gold-standard\" methods of CO measurement, as detailed in this paper (https://bjanaesthesia.org/article/S0007-0912(17)34926-7/abstract). As an increasing proportion of the experimental work at Roslin involves porcine models of human cardiovascular disease, accurate cardiac output monitoring will be become more important if these models are to be truly translational and accurately mimic a human ICU setting. The \"MostCare Up\" uses proprietary software to calculate CO according to PRAM, which as mentioned above has proven under in a variety of haemodynamic conditions and Vygon are the only UK suppliers of this monitor. (SC Ref:646142)",
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