---
title: "2306/JN - Chromatography System for Protein and Nucleic Acid Purification"
ocid: "ocds-b5fd17-19e536db-f5a4-426b-b2c7-54a1c5721a7a"
canonical_url: "https://d3tenders.com/contract/?ocid=ocds-b5fd17-19e536db-f5a4-426b-b2c7-54a1c5721a7a"
markdown_url: "https://d3tenders.com/contract/ocds-b5fd17-19e536db-f5a4-426b-b2c7-54a1c5721a7a.md"
json_url: "https://d3tenders.com/contract/ocds-b5fd17-19e536db-f5a4-426b-b2c7-54a1c5721a7a.json"
source: "Contracts Finder"
current_stage: "Award"
buyer: "UNIVERSITY OF SHEFFIELD"
published: "2019-10-14"
---

# 2306/JN - Chromatography System for Protein and Nucleic Acid Purification

Buyer: UNIVERSITY OF SHEFFIELD  
Current stage: Award  
OCID: ocds-b5fd17-19e536db-f5a4-426b-b2c7-54a1c5721a7a

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## Summary

The University of Sheffield is seeking a chromatography system for protein and nucleic acid purification through an open procurement process. The tender, titled "2306/JN - Chromatography System for Protein and Nucleic Acid Purification," falls under the goods category and is located in Sheffield, within the Yorkshire and the Humber region. The tender was published on 1st August 2019, with a closing date for submissions set for 2nd September 2019 at 12 noon UK time. The contract is valued at £65,000 and will be awarded following a competitive evaluation as part of the open procedure, which is being conducted below the threshold for EU procurement procedures.

This tender presents a significant opportunity for businesses specialising in laboratory equipment, particularly those that manufacture chromatography systems capable of various protein purification methods. Companies with expertise in affinity chromatography, anion and cation exchange, and size exclusion chromatography would be particularly well-suited to compete. Furthermore, as the equipment will serve a collaborative research group within the University, providers who can demonstrate reliability and technical capability in the life sciences sector may find this an advantageous opportunity to establish or grow their market presence.

## Notice

The Bose Lab works on understanding the function of non-coding RNA: protein complexes, and how they regulate gene expression. The group uses a combination of functional genomics, biochemistry and structural biology to probe the mechanism of protein:RNA complexes. The lab is generously funded by a Sir Henry Dale Fellowship from the Wellcome Trust and the Royal Society. The group is also associated with a wider cross-faculty and departmental grouping of labs focused on nucleic acids research within the University of Sheffield as part of the Sheffield Institute for Nucleic Acids; the equipment will therefore be of wider interest to a number of groups within the University. Our work studies how non-protein coding RNAs (ncRNAs) interact with and regulate distinct activities in regulatory enzyme complexes that control chromatin accessibility and therefore transcription in mammalian systems. We have previously shown that direct interactions with ncRNAs are a key regulatory factor for these enzymes. The biochemical and structural biology experiments carried out in the group require the formation of diverse protein:nucleic acid complexes, and their subsequent purification to high levels of purity. We also incorporate a variety of fluorophores into our purified samples. As many of these complexes are only weakly associated or transient, accurate sample preparation requires the ability to operate a number of preparation protocols quickly and reproducibly. Importantly, the ability to simultaneously detect the presence of both protein and RNA components in the sample formation reaction would be beneficial to ensure complexes are formed prior to their use in downstream experiments. The University now requires a chromatography system to support the research into this area. In order to purify proteins, RNA and protein:RNA complexes, the system must be capable of a number of distinct protein purification applications, including but not limited to: Affinity chromatography (e.g Ni/Co affinity, GST, Strep-tag), Anion and cation exchange, and size exclusion chromatography. To preserve the activity and integrity of the purified samples, the system will be housed in a climate controlled cold cabinet operated at 4C. The ability to control and monitor the system remotely would be advantageous. This is an Non-EU open exercise. The ITT can be downloaded by registering and expressing your interest on the University's e-tendering system https://in-tendhost.co.uk/sheffield If you have any questions or comments in relation to this tender they must be submitted via the In-tend system, this can be accessed at https://in-tendhost.co.uk/sheffield Completed tenders must be returned through the same e-tendering system. Closing date for receipt of tenders: 2nd September 2019 at 12 noon (UK time).

## Key Details

| Field | Value |
| --- | --- |
| Publication source | Contracts Finder |
| Latest notice | https://www.contractsfinder.service.gov.uk/Notice/e177b1c6-54df-4fa4-8cca-cd9a8463a31a |
| Notice type | Award Notice |
| Procurement type | Standard |
| Procurement category | Goods |
| Procurement method | Open |
| Procurement method details | Open procedure (below threshold) |
| Tender suitability | SME |
| Awardee scale | Large |
| All stages | Tender, Award |

## Dates

| Field | Value |
| --- | --- |
| Publication date | 14 Oct 2019 |
| Submission deadline | 2 Sep 2019 |
| Future notice date | Not specified |
| Award date | 9 Oct 2019 |
| Contract period | 20 Oct 2019 - 22 Oct 2019 |
| Recurrence | Not specified |

## Values

| Field | Value |
| --- | --- |
| Tender value | £65,000 |
| Lots value | Not specified |
| Awards value | £65,000 |
| Contracts value | Not specified |

## Status

| Field | Value |
| --- | --- |
| Tender status | Complete |
| Lots status | Not specified |
| Awards status | Active |
| Contracts status | Not specified |

## Buyer

| Field | Value |
| --- | --- |
| Main buyer | UNIVERSITY OF SHEFFIELD |
| Locality | SHEFFIELD |
| Post town | Sheffield |
| Postcode | S10 2TN |
| Country | England |
| ITL 1 | TLE Yorkshire and The Humber |
| ITL 2 | TLE3 South Yorkshire |
| ITL 3 | TLE32 Sheffield |
| Local authority | Sheffield |
| Electoral ward | Broomhill and Sharrow Vale |
| Westminster constituency | Sheffield Central |
| Delivery location | TLE Yorkshire and The Humber |

## Supplier

| Field | Value |
| --- | --- |
| Number of suppliers | 1 |
| Supplier names | GE HEALTHCARE |

## CPV Codes

### Divisions

- 38 - Laboratory, optical and precision equipments (excl. glasses)

### Codes

- 38432200 - Chromatographs

## Release History

- 14 Oct 2019 at 10:32 - Award - Award Notice - https://www.contractsfinder.service.gov.uk/Notice/e177b1c6-54df-4fa4-8cca-cd9a8463a31a
- 1 Aug 2019 at 10:55 - Tender - Tender Notice - https://www.contractsfinder.service.gov.uk/Notice/8e070b5f-a638-432e-8b83-d8a7f47e3ee1

## Documents

- https://www.contractsfinder.service.gov.uk/Notice/e177b1c6-54df-4fa4-8cca-cd9a8463a31a
  14th October 2019 - Awarded contract notice on Contracts Finder
- https://www.contractsfinder.service.gov.uk/Notice/8e070b5f-a638-432e-8b83-d8a7f47e3ee1
  1st August 2019 - Opportunity notice on Contracts Finder
- https://in-tendhost.co.uk/sheffield
  All tender documents are available at:

## Provenance

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