--- title: "GOSH - NHS GMS Alliance ctDNA national transformation project Health Economics" ocid: "ocds-b5fd17-3c9302c0-a391-4936-a6ff-604924b9cbb1" canonical_url: "https://d3tenders.com/contract/?ocid=ocds-b5fd17-3c9302c0-a391-4936-a6ff-604924b9cbb1" markdown_url: "https://d3tenders.com/contract/ocds-b5fd17-3c9302c0-a391-4936-a6ff-604924b9cbb1.md" json_url: "https://d3tenders.com/contract/ocds-b5fd17-3c9302c0-a391-4936-a6ff-604924b9cbb1.json" source: "Contracts Finder" current_stage: "Tender" buyer: "GREAT ORMOND STREET HOSPITAL FOR CHILDREN NHS FOUNDATION TRUST" published: "2023-01-03" --- # GOSH - NHS GMS Alliance ctDNA national transformation project Health Economics Buyer: GREAT ORMOND STREET HOSPITAL FOR CHILDREN NHS FOUNDATION TRUST Current stage: Tender OCID: ocds-b5fd17-3c9302c0-a391-4936-a6ff-604924b9cbb1 [View canonical contract page](https://d3tenders.com/contract/?ocid=ocds-b5fd17-3c9302c0-a391-4936-a6ff-604924b9cbb1) [Download OCDS JSON](https://d3tenders.com/contract/ocds-b5fd17-3c9302c0-a391-4936-a6ff-604924b9cbb1.json) ## Summary The Great Ormond Street Hospital for Children NHS Foundation Trust has initiated a tender titled "GOSH - NHS GMS Alliance ctDNA national transformation project Health Economics" within the Research laboratory services industry category. The procurement method being used is an Open procedure (below threshold), with a contract period starting on March 1, 2023, and ending on December 31, 2023. The tender's value is £150,000, with a tender period deadline set for January 20, 2023, at 12:00:00 UTC. The project involves exploring ctDNA testing for suspected stage 3/4 non-small cell lung cancer patients in London, United Kingdom. This tender from Great Ormond Street Hospital for Children NHS Foundation Trust presents an opportunity for small and medium-sized enterprises (SMEs) and voluntary, community and social enterprise (VCSE) organisations to engage in a health economics evaluation project related to liquid biopsy testing. Businesses in the healthcare or laboratory services sectors with an interest in genomic testing and cancer research would be well-suited to compete for this tender and contribute to the evidence base for the further roll out of ctDNA testing in the NHS. ## Notice The NHS Genomic Medicine Service infrastructure, including the seven Genomic Laboratory Hubs (GLHs), enable the full repertoire of genomics testing for cancer patients in the NHS in England as outlined in the National Genomic Test Directory (Test Directory). Most of the somatic cancer testing in the Test Directory is based on testing the genetic make-up of an individual's tumour. This requires a tumour sample to be taken and then sent to the GLHs for testing. Increasingly it is becoming possible to use blood samples to test the circulating free DNA (cfDNA) for the presence of disease-causing mutations in circulating tumour DNA (ctDNA), also known as liquid biopsy testing. ctDNA based testing has now been validated, pan-cancer, in a number of different trials including I-SPY2, FLAUAS, AURA3, SCRUM-Japan, GOZILA, GRECO, MYSTIC, PEGASUS, COBRA, SOLAR1 and plasmaMATCH. ctDNA testing for EGFR gene mutations is already included on the Test Directory for lung cancer patients. To build the evidence base for the further roll out of ctDNA testing in the NHS, NHS England convened a group of experts to scope a project to explore ctDNA starting with suspected stage 3/4 non-small cell lung cancer patients. ctDNA samples will be taken from at least 700 patients with suspected thoracic malignancy without a confirmed histological diagnosis of stage 3/4 non-small cell lung cancer for direct gene panel analysis for those genes already approved on the Test Directory. ctDNA samples taken prior to the start of this project for patients with non-small cell lung cancer taken at the same time as tissue biopsy or after histological verification in parallel to tissue molecular analyses will also be included in this health economics evaluation. Numbers to be confirmed. We publish all our opportunities on the Health Family eCommercial System https://health-family.force.com/s/Welcome ## Key Details | Field | Value | | --- | --- | | Publication source | Contracts Finder | | Latest notice | https://www.contractsfinder.service.gov.uk/Notice/f42177c1-154a-4a45-b595-e8ae42dad6c3 | | Notice type | Tender Notice | | Procurement type | Standard | | Procurement category | Not specified | | Procurement method | Open | | Procurement method details | Open procedure (below threshold) | | Tender suitability | SME, VCSE | | Awardee scale | Not specified | | All stages | Tender | ## Dates | Field | Value | | --- | --- | | Publication date | 3 Jan 2023 | | Submission deadline | 20 Jan 2023 | | Future notice date | Not specified | | Award date | Not specified | | Contract period | 1 Mar 2023 - 31 Dec 2023 | | Recurrence | Not specified | ## Values | Field | Value | | --- | --- | | Tender value | £150,000 | | Lots value | Not specified | | Awards value | Not specified | | Contracts value | Not specified | ## Status | Field | Value | | --- | --- | | Tender status | Active | | Lots status | Not specified | | Awards status | Not specified | | Contracts status | Not specified | ## Buyer | Field | Value | | --- | --- | | Main buyer | GREAT ORMOND STREET HOSPITAL FOR CHILDREN NHS FOUNDATION TRUST | | Locality | LONDON | | Post town | South East London | | Postcode | SE1 4BY | | Country | England | | ITL 1 | TLI London | | ITL 2 | TLI4 Inner London - East | | ITL 3 | TLI44 Lewisham and Southwark | | Local authority | Southwark | | Electoral ward | Chaucer | | Westminster constituency | Bermondsey and Old Southwark | | Delivery location | TLI London | ## CPV Codes ### Divisions - 73 - Research and development services and related consultancy services ### Codes - 73111000 - Research laboratory services ## Release History - 3 Jan 2023 at 10:22 - Tender - Tender Notice - https://www.contractsfinder.service.gov.uk/Notice/f42177c1-154a-4a45-b595-e8ae42dad6c3 - 3 Jan 2023 at 10:03 - Tender - Tender Notice - https://www.contractsfinder.service.gov.uk/Notice/e006bf3e-4d91-4f8c-8de7-a4e79fed6c43 ## Documents - https://www.contractsfinder.service.gov.uk/Notice/f42177c1-154a-4a45-b595-e8ae42dad6c3 3rd January 2023 - Opportunity notice on Contracts Finder - https://www.contractsfinder.service.gov.uk/Notice/e006bf3e-4d91-4f8c-8de7-a4e79fed6c43 3rd January 2023 - Opportunity notice on Contracts Finder ## Notice URLs - https://health-family.force.com/s/Welcome ## Provenance This Markdown file is an alternate public rendering of the D3 Tenders contract record. The canonical page is https://d3tenders.com/contract/?ocid=ocds-b5fd17-3c9302c0-a391-4936-a6ff-604924b9cbb1. The underlying structured data is available as OCDS JSON at https://d3tenders.com/contract/ocds-b5fd17-3c9302c0-a391-4936-a6ff-604924b9cbb1.json.