--- title: "Q Fever collection of patient serum" ocid: "ocds-b5fd17-3da44687-ed61-4130-bc6f-627217002010" canonical_url: "https://d3tenders.com/contract/?ocid=ocds-b5fd17-3da44687-ed61-4130-bc6f-627217002010" markdown_url: "https://d3tenders.com/contract/ocds-b5fd17-3da44687-ed61-4130-bc6f-627217002010.md" json_url: "https://d3tenders.com/contract/ocds-b5fd17-3da44687-ed61-4130-bc6f-627217002010.json" source: "Contracts Finder" current_stage: "Planning" buyer: "MHRA BUYER ORGANISATION" published: "2019-03-15" --- # Q Fever collection of patient serum Buyer: MHRA BUYER ORGANISATION Current stage: Planning OCID: ocds-b5fd17-3da44687-ed61-4130-bc6f-627217002010 [View canonical contract page](https://d3tenders.com/contract/?ocid=ocds-b5fd17-3da44687-ed61-4130-bc6f-627217002010) [Download OCDS JSON](https://d3tenders.com/contract/ocds-b5fd17-3da44687-ed61-4130-bc6f-627217002010.json) ## Summary The MHRA Buyer Organisation is currently in the planning stage of a procurement process titled "Q Fever collection of patient serum". This initiative falls under the diagnostics industry category, specifically aiming to establish a human reference serum for Q fever by collecting patient serum samples. Located in the East of England, the engagement for potential suppliers will conclude on 5th April 2019, by which time interested parties must register their interest via email. A direct award may occur if no suitable submissions are received by the deadline. This tender presents significant growth opportunities for suppliers in the medical and laboratory services sectors, particularly those with expertise in clinical chemistry and microbiological cultures. Companies capable of accessing a wide network for participant recruitment and possessing the necessary laboratory capabilities to handle and test biological samples will find this tender especially suited to their services. With potential direct award implications, those able to meet the stringent requirements outlined are encouraged to demonstrate their qualifications promptly. ## Notice The agency is planning to establish a human reference serum containing anti-C. burnetii IgG and IgM antibodies, with the objective to validate this material as a WHO international standard. To establish this human reference serum, we require the collection of serum that meets the inclusion criteria detailed below. Suppliers that can meet the requirements below are invited to register their interest for the supply and testing of serum samples for the development of a WHO standard for Q fever. Suppliers must be able to: 1. Evaluate the exact requirements for the development of a WHO standard for Q fever. To enable this in a timely fashion, the supplier should have an established network in the Q fever community to engage with 2. Identify subjects with different stages of Q fever infection (convalescing, actively infected or very recent (chronic) infection) 3. Access a large collection of banked samples from a well characterised cohort of past Q fever (exposed) patients for selection of convalescing subjects 4. Actively recruit subjects with active or very recent infection (unless already identified through recent/ongoing efforts) 5. Selected subjects should be aware that serum may be characterised and evaluated in an in vivo potency model for experimental vaccines. 6. Re-test /verify sero-positivity in selected patient to ensure fitness for purpose for this study (seropositivity confirmed by the most commonly used laboratory assays (IFA, ELISA, CFT) 7. Characterize donors with independent measures (other than serology) for confirmation of exposure to C. burnetii, such as PCR, IGRA or testing for cellular recall responses 8. Select at least 5 appropriate donors (defined in the evaluation) for large volume serum collection 9. Arrange plasmapheresis of the 5 donors 10. Prepare serum from donor samples 11. Test/arrange testing of serum samples for blood borne pathogens (HIV, HBV and HCV) 12. Supply NIBSC with a small sample, 25mL, for additional testing 13. Ship 500 ml serum samples from each donor to NIBSC The supplier should have the capability of supplying the collected and tested Q fever seropositive samples within 6 months of establishing the requirements. As far as we are aware there is only one supplier who is able to meet this very specific request. Potential suppliers if they feel they can meet the requirement should email Nawaz.habib@nibsc.org to register an interest. If no submissions of potential interest are received by close of play 5th April 2019, it is then intended to perform a direct award without competition to the sole supplier we believe can deliver the required service. ## Key Details | Field | Value | | --- | --- | | Publication source | Contracts Finder | | Latest notice | https://www.contractsfinder.service.gov.uk/Notice/1840c47d-5fc1-4c3f-9b96-26151d7f005c | | Notice type | Market Engagement Notice | | Procurement type | Standard | | Procurement category | Not specified | | Procurement method | Not Specified | | Procurement method details | Not specified | | Tender suitability | Not specified | | Awardee scale | Not specified | | All stages | Planning | ## Dates | Field | Value | | --- | --- | | Publication date | 15 Mar 2019 | | Submission deadline | Not specified | | Future notice date | 5 Apr 2019 | | Award date | Not specified | | Contract period | Not specified | | Recurrence | Not specified | ## Values | Field | Value | | --- | --- | | Tender value | Not specified | | Lots value | Not specified | | Awards value | Not specified | | Contracts value | Not specified | ## Status | Field | Value | | --- | --- | | Tender status | Planning | | Lots status | Not specified | | Awards status | Not specified | | Contracts status | Not specified | ## Buyer | Field | Value | | --- | --- | | Main buyer | MHRA BUYER ORGANISATION | | Locality | POTTERS BAR | | Post town | Enfield | | Postcode | EN6 3QG | | Country | England | | ITL 1 | TLH East (England) | | ITL 2 | TLH2 Bedfordshire and Hertfordshire | | ITL 3 | TLH27 South West Hertfordshire | | Local authority | Hertsmere | | Electoral ward | Shenley | | Westminster constituency | Hertsmere | | Delivery location | Not specified | ## CPV Codes ### Divisions - 33 - Medical equipments, pharmaceuticals and personal care products - 71 - Architectural, construction, engineering and inspection services - 73 - Research and development services and related consultancy services - 85 - Health and social work services ### Codes - 33124000 - Diagnostics and radiodiagnostic devices and supplies - 33141560 - Human organs - 33141570 - Human blood - 33159000 - Clinical chemistry system - 33698100 - Microbiological cultures - 71900000 - Laboratory services - 73110000 - Research services - 73111000 - Research laboratory services - 85121200 - Medical specialist services ## Release History - 15 Mar 2019 at 13:25 - Planning - Market Engagement Notice - https://www.contractsfinder.service.gov.uk/Notice/1840c47d-5fc1-4c3f-9b96-26151d7f005c ## Documents - https://www.contractsfinder.service.gov.uk/Notice/1840c47d-5fc1-4c3f-9b96-26151d7f005c 15th March 2019 - Early engagement notice on Contracts Finder - https://mhra.bravosolution.co.uk/web_mhra/login.html MHRA bravo etendering portal Weblink ## Provenance This Markdown file is an alternate public rendering of the D3 Tenders contract record. The canonical page is https://d3tenders.com/contract/?ocid=ocds-b5fd17-3da44687-ed61-4130-bc6f-627217002010. The underlying structured data is available as OCDS JSON at https://d3tenders.com/contract/ocds-b5fd17-3da44687-ed61-4130-bc6f-627217002010.json.