--- title: "Tender for the Supply and Installation of FRET/Ca2+ Imaging and 4-Camera TIRF Microscopes to the University of Birmingham" ocid: "ocds-b5fd17-b8617a13-d753-4ae0-bb38-3c8519134d29" canonical_url: "https://d3tenders.com/contract/?ocid=ocds-b5fd17-b8617a13-d753-4ae0-bb38-3c8519134d29" markdown_url: "https://d3tenders.com/contract/ocds-b5fd17-b8617a13-d753-4ae0-bb38-3c8519134d29.md" json_url: "https://d3tenders.com/contract/ocds-b5fd17-b8617a13-d753-4ae0-bb38-3c8519134d29.json" source: "Contracts Finder" current_stage: "Tender" buyer: "UNIVERSITY OF BIRMINGHAM" published: "2017-10-20" --- # Tender for the Supply and Installation of FRET/Ca2+ Imaging and 4-Camera TIRF Microscopes to the University of Birmingham Buyer: UNIVERSITY OF BIRMINGHAM Current stage: Tender OCID: ocds-b5fd17-b8617a13-d753-4ae0-bb38-3c8519134d29 [View canonical contract page](https://d3tenders.com/contract/?ocid=ocds-b5fd17-b8617a13-d753-4ae0-bb38-3c8519134d29) [Download OCDS JSON](https://d3tenders.com/contract/ocds-b5fd17-b8617a13-d753-4ae0-bb38-3c8519134d29.json) ## Summary The University of Birmingham is currently seeking tenders for the supply and installation of advanced FRET/Ca2+ imaging and 4-camera TIRF microscopes for the Institute of Metabolism and Systems Research (IMSR). This procurement falls under the goods category, specifically within the microscopes industry (CPV code: 38510000). The tender is in the active stage and is being conducted using an open procurement method. The tender period will close on 20th November 2017, with the contract expected to start on 19th December 2017 and run until 29th June 2018, taking place in Edgbaston, West Midlands, United Kingdom. This tender presents a significant opportunity for businesses specialising in scientific equipment and technology, particularly for those with expertise in advanced imaging systems. Small and medium-sized enterprises (SMEs) are encouraged to apply, especially those that can provide cutting-edge microscopy solutions tailored to the needs of the academic and research sectors. Companies involved in manufacturing or supplying high-sensitivity imaging technology with flexible user-friendly software and high-performance components will be well-suited to compete in this process. ## Notice The FRET/Ca2+ imaging and 4-camera TIRF microscopes are to be purchased by the Institute of Metabolism and Systems Research (IMSR), UoB. Match funding will be provided through COMPARE (http://www.birmingham-nottingham.ac.uk/compare/index.aspx). The systems will be housed in the recently refurbished rooms of the Centre of Membrane Proteins and Receptors (COMPARE). Access will be granted to members of COMPARE, as well as the intravital microscopy (IVM) user group. The specification below specifications outline the requirements for: a. A FRET/Ca2+ imaging microscope, which must be capable of performing fast high-sensitivity ratiometric imaging and photometric measurements in cells expressing FRET reporters or loaded with Ca2+ indictors (e.g. Fura-2). The system should be equipped with a monochromator for maximal flexibility and speed in the selection of the excitation wavelength, a dual-camera beam splitter, a very high sensitivity camera (EMCCD or equivalent). In addition, it should be equipped with a photomultiplier-based ratiometric acquisition system allowing ultrafast kinetics measurements (up to 100 microsecond temporal resolution). The system should also be equipped with a caged incubator for temperature control and a laminar-flow superfusion system (or more if needed) with compatible imaging chamber allowing both ultrarapid exchange of solutions (< 2 ms) and long superfusion times (up to 1 hour). The perfusion systems/imaging chambers/stage insets should be ideally interchangeable and could be shared between the two microscopes, allowing maximal flexibility. The microscope should be controlled by a user-friendly software, allowing the real-time monitoring of ratiometric FRET and Ca2+ traces and the control/recording of the triggers to/from the perfusion system(s). b. A 4-channel 2D/3D TIRF microscope for the analysis of both fast and slow dynamic biological processes (from few milliseconds to 1 hour) in living cells by single-molecule microscopy/single-particle tracking, superresolution microscopy methods such as 2D/3D PALM/dSTORM and single-molecule FRET. The system should also allow the fast and simultaneous acquisition of FRET between CFP and YFP by ratiometric imaging and single-molecule acquisition in the red or far-red channel. The system should also ideally allow to perform FRAP and/or uncaging experiments. The system should be equipped with suitable solid-state lasers of adequate power, a TIRF illuminator providing homogenous illumination, a quadruple camera beam-splitter and four fast EMCCD cameras. The microscope should be controlled by a user-friendly software, allowing fast synchronised real-time acquisition from the four cameras (>= 56 frames/s in normal full-frame 512x512 mode and >= 560 frames/s from a 128x128 sub-array in crop mode). The system should also be equipped with a caged incubator for temperature control and a laminar-flow superfusion system (or more if needed) with compatible imaging chambe... Additional information: Please log in or register to find documents at www.in-tendhost.com/universityofbirmingham Is a Recurrent Procurement Type? : No ## Key Details | Field | Value | | --- | --- | | Publication source | Contracts Finder | | Latest notice | https://www.contractsfinder.service.gov.uk/Notice/d49a247a-62f3-47f8-80ac-6bab1a33c272 | | Notice type | Tender Notice | | Procurement type | Standard | | Procurement category | Goods | | Procurement method | Open | | Procurement method details | Open procedure (above threshold) | | Tender suitability | SME | | Awardee scale | Not specified | | All stages | Tender | ## Dates | Field | Value | | --- | --- | | Publication date | 20 Oct 2017 | | Submission deadline | 20 Nov 2017 | | Future notice date | Not specified | | Award date | Not specified | | Contract period | 19 Dec 2017 - 29 Jun 2018 | | Recurrence | Not specified | ## Values | Field | Value | | --- | --- | | Tender value | Not specified | | Lots value | Not specified | | Awards value | Not specified | | Contracts value | Not specified | ## Status | Field | Value | | --- | --- | | Tender status | Active | | Lots status | Not specified | | Awards status | Not specified | | Contracts status | Not specified | ## Buyer | Field | Value | | --- | --- | | Main buyer | UNIVERSITY OF BIRMINGHAM | | Locality | EDGBASTON | | Post town | Birmingham | | Postcode | B15 2TT | | Country | England | | ITL 1 | TLG West Midlands (England) | | ITL 2 | TLG3 West Midlands | | ITL 3 | TLG31 Birmingham | | Local authority | Birmingham | | Electoral ward | Edgbaston | | Westminster constituency | Birmingham Edgbaston | | Delivery location | TLG West Midlands (England) | ## CPV Codes ### Divisions - 38 - Laboratory, optical and precision equipments (excl. glasses) ### Codes - 38510000 - Microscopes ## Release History - 20 Oct 2017 at 14:22 - TenderAmendment - Tender Notice - https://www.contractsfinder.service.gov.uk/Notice/d49a247a-62f3-47f8-80ac-6bab1a33c272 - 20 Oct 2017 at 14:22 - Tender - Tender Notice - https://www.contractsfinder.service.gov.uk/Notice/d49a247a-62f3-47f8-80ac-6bab1a33c272 ## Documents - https://www.contractsfinder.service.gov.uk/Notice/d49a247a-62f3-47f8-80ac-6bab1a33c272 20th October 2017 - Opportunity notice on Contracts Finder - https://in-tendhost.co.uk/universityofbirmingham/aspx/ Additional information on how to apply for this contract ## Notice URLs - http://www.birmingham-nottingham.ac.uk/compare/index.aspx ## Provenance This Markdown file is an alternate public rendering of the D3 Tenders contract record. The canonical page is https://d3tenders.com/contract/?ocid=ocds-b5fd17-b8617a13-d753-4ae0-bb38-3c8519134d29. The underlying structured data is available as OCDS JSON at https://d3tenders.com/contract/ocds-b5fd17-b8617a13-d753-4ae0-bb38-3c8519134d29.json.