--- title: "RFQ - Prototype Novel Dosimeter for FLASH Radiotherapy" ocid: "ocds-b5fd17-da356af1-1707-4452-9504-5a7238d58391" canonical_url: "https://d3tenders.com/contract/?ocid=ocds-b5fd17-da356af1-1707-4452-9504-5a7238d58391" markdown_url: "https://d3tenders.com/contract/ocds-b5fd17-da356af1-1707-4452-9504-5a7238d58391.md" json_url: "https://d3tenders.com/contract/ocds-b5fd17-da356af1-1707-4452-9504-5a7238d58391.json" source: "Contracts Finder" current_stage: "Tender" buyer: "NATIONAL PHYSICAL LABORATORY" published: "2024-01-29" --- # RFQ - Prototype Novel Dosimeter for FLASH Radiotherapy Buyer: NATIONAL PHYSICAL LABORATORY Current stage: Tender OCID: ocds-b5fd17-da356af1-1707-4452-9504-5a7238d58391 [View canonical contract page](https://d3tenders.com/contract/?ocid=ocds-b5fd17-da356af1-1707-4452-9504-5a7238d58391) [Download OCDS JSON](https://d3tenders.com/contract/ocds-b5fd17-da356af1-1707-4452-9504-5a7238d58391.json) ## Summary The National Physical Laboratory is seeking competitive quotations for the procurement of a prototype novel dosimeter for FLASH radiotherapy. This opportunity falls under the industry category of laboratory, optical, and precision equipment. The tender is in the form of a limited procurement method with a tender period ending on 12th February 2024. The contract period is set to start on 4th March 2024 and end on 31st July 2025, with delivery addresses in London, United Kingdom. This tender presents an opportunity for SMEs in the goods sector to engage in the development of innovative radiation therapy equipment. Businesses with expertise in precision equipment design and manufacturing would be well-suited to compete in this procurement process. The objective is to advance the Transmission Calorimeter system to Technology Readiness Level 5, focusing on proof-of-concept development rather than clinical product production. ## Notice Recent advancements in radiation therapy, particularly the emergence of UHDR or FLASH-RT (Ultra-High Dose Rate Radiotherapy), have introduced a new set of complexities. FLASH-RT involves the delivery of radiation at remarkably elevated dose rates, exceeding 40 Gy/s. This revolutionary approach has demonstrated the potential to spare healthy tissues while effectively treating cancerous cells. It offers the promise of reduced side effects, shorter treatment times, and greater access to therapy. Unlike traditional ionisation chambers used in radiation dosimetry, the Transmission Calorimeter does not rely on ionization processes. Instead, it exploits the rise in temperature induced by absorption of the radiation beam. By accurately measuring this temperature increase, the Transmission Calorimeter provides a direct method for quantifying the radiation dose delivered to a target area. The Transmission Calorimeter system consists of two forms of device that need to be designed, manufactured, and assembled. These are: a. Electronic Readout Box: This box contains four DC Wheatstone Bridge circuits, each fed by a voltage regulator. It has panel mounted connectors to facilitate connection to the thermistor networks located within the Transmission Calorimeter and to enable monitoring of the "Bridge Out of Balance" Voltages, measured using external voltmeters and integrated Analogue to Digital Converters (ADCs). b. Radiation Sensor: This consists of two printed circuit boards (PCBs) and serves as the primary platform for thermal measurements. It is composed of two modules, the "active" and "compensating" areas. The Radiation Sensor will connect to the Electronic Readout Box. Several different sizes of Radiation Sensors are requested as part of this procurement process. A successful patent application has been made for the Radiation Sensor by NPL Management Ltd, WO2023227909A1 "TRANSMISSION CALORIMETER FOR MEASURING DOSE OF RADIATION", has been published and is accessible on patent databases. https://worldwide.espacenet.com/patent/search/family/082324167/publication/WO2023227909A1?q=WO2023227909 This may be referenced by Bidders for additional context. The project has secured funding from the UK Government Office for Technology Transfer (GOTT) to explore the commercial potential of NPL-held intellectual property related to the Transmission Calorimeter. The primary objective is to develop an 'advanced prototype' of the Transmission Calorimeter system. The current stage of development is estimated to be at Technology Readiness Level (TRL) 3, signifying a proof-of-concept stage. The project aims to advance the system to TRL 5 or higher, demonstrating its viability as an advanced prototype. It's essential to emphasise that the project does not intend to produce a clinical product for measuring radiation dose. Instead, the focus is on enhancing confidence in the Transmission Calorimeter concept. Additional information: The Authority is using the LUPC Bravo e-Procurement portal to conduct the procurement process. All Suppliers must register their company via the LUPC Bravo Portal. ## Key Details | Field | Value | | --- | --- | | Publication source | Contracts Finder | | Latest notice | https://www.contractsfinder.service.gov.uk/Notice/878bb3d6-b297-46de-a8f1-45c47f51ef95 | | Notice type | Tender Notice | | Procurement type | Standard | | Procurement category | Goods | | Procurement method | Limited | | Procurement method details | Competitive quotation (below threshold) | | Tender suitability | SME | | Awardee scale | Not specified | | All stages | Tender | ## Dates | Field | Value | | --- | --- | | Publication date | 29 Jan 2024 | | Submission deadline | 12 Feb 2024 | | Future notice date | Not specified | | Award date | Not specified | | Contract period | 4 Mar 2024 - 31 Jul 2025 | | Recurrence | Not specified | ## Values | Field | Value | | --- | --- | | Tender value | Not specified | | Lots value | Not specified | | Awards value | Not specified | | Contracts value | Not specified | ## Status | Field | Value | | --- | --- | | Tender status | Active | | Lots status | Not specified | | Awards status | Not specified | | Contracts status | Not specified | ## Buyer | Field | Value | | --- | --- | | Main buyer | NATIONAL PHYSICAL LABORATORY | | Locality | TEDDINGTON | | Post town | Twickenham | | Postcode | TW11 0LW | | Country | England | | ITL 1 | TLI London | | ITL 2 | TLI7 Outer London - West and North West | | ITL 3 | TLI75 Hounslow and Richmond upon Thames | | Local authority | Richmond upon Thames | | Electoral ward | Teddington | | Westminster constituency | Twickenham | | Delivery location | TLI London | ## CPV Codes ### Divisions - 38 - Laboratory, optical and precision equipments (excl. glasses) ### Codes - 38000000 - Laboratory, optical and precision equipments (excl. glasses) ## Release History - 29 Jan 2024 at 12:05 - Tender - Tender Notice - https://www.contractsfinder.service.gov.uk/Notice/878bb3d6-b297-46de-a8f1-45c47f51ef95 ## Documents - https://www.contractsfinder.service.gov.uk/Notice/878bb3d6-b297-46de-a8f1-45c47f51ef95 29th January 2024 - Opportunity notice on Contracts Finder - https://lupc.bravosolution.co.uk/web/login.shtml LUPC Bravo e-Tendering portal ## Notice URLs - https://worldwide.espacenet.com/patent/search/family/082324167/publication/WO2023227909A1?q=WO2023227909 ## Provenance This Markdown file is an alternate public rendering of the D3 Tenders contract record. The canonical page is https://d3tenders.com/contract/?ocid=ocds-b5fd17-da356af1-1707-4452-9504-5a7238d58391. The underlying structured data is available as OCDS JSON at https://d3tenders.com/contract/ocds-b5fd17-da356af1-1707-4452-9504-5a7238d58391.json.