---
title: "Investigation of bacterial involvement in canine CRGV cases"
ocid: "ocds-b5fd17-ec9dc124-696d-441a-9f42-c16ffe0310fe"
canonical_url: "https://d3tenders.com/contract/?ocid=ocds-b5fd17-ec9dc124-696d-441a-9f42-c16ffe0310fe"
markdown_url: "https://d3tenders.com/contract/ocds-b5fd17-ec9dc124-696d-441a-9f42-c16ffe0310fe.md"
json_url: "https://d3tenders.com/contract/ocds-b5fd17-ec9dc124-696d-441a-9f42-c16ffe0310fe.json"
source: "Contracts Finder"
current_stage: "Award"
buyer: "DEFRA NETWORK ETENDERING PORTAL"
published: "2020-04-20"
---

# Investigation of bacterial involvement in canine CRGV cases

Buyer: DEFRA NETWORK ETENDERING PORTAL  
Current stage: Award  
OCID: ocds-b5fd17-ec9dc124-696d-441a-9f42-c16ffe0310fe

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## Summary

The procurement process for the "Investigation of bacterial involvement in canine CRGV cases" is conducted by the Defra Network eTendering Portal. This initiative falls under the research and development services category, located in the UK. The procurement stage is at the award phase, with the contract value set at £25,000, awarded on 10th February 2020. The contract period commenced on 1st November 2019 and is scheduled to conclude by 31st March 2020. Interested suppliers should note that the procurement method employed was a direct procurement through a single tender action, as it was deemed below the threshold for competition.

This tender presents viable opportunities for businesses that specialise in veterinary research, microbiology, or health consultancy, particularly those capable of investigating bacterial diseases affecting canines. Small and medium-sized enterprises (SMEs) within these fields would be particularly well-suited to compete for this contract, given the emphasis on specialised knowledge regarding diseases such as canine cutaneous and renal glomerular vasculopathy (CRGV). Businesses with the capability to conduct scientific research and those offering innovative solutions in veterinary health are encouraged to consider engaging with future procurement opportunities in this area.

## Notice

Canine cutaneous and renal glomerular vasculopathy (CRGV and sometimes known as 'Alabama rot') in the UK first appeared in 2012, with 4 cases presenting to a Anderson Moores from practices around the New Forest, Hampshire with acute kidney injury (AKI) and skin lesions. The numbers of cases and geographical distribution of the disease have in the main increased year on year, with 190 cases now reported. The disease is normally characterised by the initial appearance of skin lesions on the limbs +/- face and body. Some dogs then go on to develop acute deterioration of kidney function and death. On post mortem blood vessels are seen to be blocked by thrombi (clots). The cause of the disease is unknown, despite investigation. Tests undertaken include investigation for E.coli (given some similarities to human haemolytic uremic syndrome), Circovirus, pan viral metagenomics and bacterial 16S probes, heavy metals and ethylene glycol poisoning. Leptospira has been investigated as a cause, and although presence of this organism was high in cases, results couldn't indicate a causative link. Despite the extensive investigations already undertaken, a few bacterial causes remain possible based upon experimental results or pathological findings. Toxigenic bacteria have not been found in the kidneys, but this does not rule out their presence in the skin lesions, with local production of toxins into the circulation causing subsequent kidney injury. Shiga toxigenic E. coli were hypothesised to cause similar disease in the USA with kidney injury. Aeromonas hydrophilia causes similar skin lesions in fish and amphibians with subsequent kidney failure, as well as disease in humans, and are also toxigenic, with toxin production in limbs causing organ injury. Leptospira were unusually prevalent in cases and can cause kidney injury. Without an analysis of cases vs healthy animals it is impossible to confirm the likely association of these bacteria (Aeromonas, E.coli and Leptospira Additional information: Please note that Defra procurement uses an E-tendering system for Procurement activities. This is currently provided by Bravo Solutions. To access appropriate tendering and contractual documents, please access the E-Tendering portal at https://defra.bravosolution.co.uk", ensuring that your registration includes "Defra". If you have any problems with this system, please contact Bravo on their telephone helpline number 0800 368 4850 or by emailing them at help@bravosolution.co.uk. "

## Key Details

| Field | Value |
| --- | --- |
| Publication source | Contracts Finder |
| Latest notice | https://www.contractsfinder.service.gov.uk/Notice/6e222e4d-4d48-4081-b335-053e0aba96d7 |
| Notice type | Award Notice |
| Procurement type | Standard |
| Procurement category | Services |
| Procurement method | Direct |
| Procurement method details | Single tender action (below threshold) |
| Tender suitability | SME |
| Awardee scale | Large |
| All stages | Award |

## Dates

| Field | Value |
| --- | --- |
| Publication date | 20 Apr 2020 |
| Submission deadline | 1 Oct 2019 |
| Future notice date | Not specified |
| Award date | 10 Feb 2020 |
| Contract period | 1 Nov 2019 - 31 Mar 2020 |
| Recurrence | Not specified |

## Values

| Field | Value |
| --- | --- |
| Tender value | Not specified |
| Lots value | Not specified |
| Awards value | £25,000 |
| Contracts value | Not specified |

## Status

| Field | Value |
| --- | --- |
| Tender status | Complete |
| Lots status | Not specified |
| Awards status | Active |
| Contracts status | Not specified |

## Buyer

| Field | Value |
| --- | --- |
| Main buyer | DEFRA NETWORK ETENDERING PORTAL |
| Locality | LONDON |
| Post town | South West London |
| Postcode | SW1P 3JR |
| Country | England |
| ITL 1 | TLI London |
| ITL 2 | TLI3 Inner London - West |
| ITL 3 | TLI35 Westminster and City of London |
| Local authority | Westminster |
| Electoral ward | St James's |
| Westminster constituency | Cities of London and Westminster |
| Delivery location | Not specified |

## Supplier

| Field | Value |
| --- | --- |
| Number of suppliers | 1 |
| Supplier names | UNIVERSITY OF BRISTOL |

## CPV Codes

### Divisions

- 73 - Research and development services and related consultancy services

### Codes

- 73000000 - Research and development services and related consultancy services

## Release History

- 20 Apr 2020 at 10:58 - Award - Award Notice - https://www.contractsfinder.service.gov.uk/Notice/6e222e4d-4d48-4081-b335-053e0aba96d7

## Documents

- https://www.contractsfinder.service.gov.uk/Notice/6e222e4d-4d48-4081-b335-053e0aba96d7
  20th April 2020 - Awarded contract notice on Contracts Finder
- https://www.contractsfinder.service.gov.uk/Notice/Attachment/e15130d3-bad9-498c-90fb-d655a09b397f
  n/a
- https://defra.bravosolution.co.uk
  E-Tendering portal help

## Provenance

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