---
title: "Supply and Manufacture of Investigational Medicinal Products (IMPs) for the Clinical Trial: \"Examining Antibiotics for Ulcerated Skin Cancer Surgical Excision\""
ocid: "ocds-h6vhtk-04d494"
canonical_url: "https://d3tenders.com/contract/?ocid=ocds-h6vhtk-04d494"
markdown_url: "https://d3tenders.com/contract/ocds-h6vhtk-04d494.md"
json_url: "https://d3tenders.com/contract/ocds-h6vhtk-04d494.json"
source: "Find A Tender Service"
current_stage: "Award"
buyer: "NHS WALES SHARED SERVICES PARTNERSHIP (NWSSP) - PROCUREMENT SERVICES"
published: "2025-01-20"
---

# Supply and Manufacture of Investigational Medicinal Products (IMPs) for the Clinical Trial: "Examining Antibiotics for Ulcerated Skin Cancer Surgical Excision"

Buyer: NHS WALES SHARED SERVICES PARTNERSHIP (NWSSP) - PROCUREMENT SERVICES  
Current stage: Award  
OCID: ocds-h6vhtk-04d494

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## Summary

NHS Wales Shared Services Partnership (NWSSP) - Procurement Services has completed a procurement process for Cardiff and Vale University Health Board, based in Cardiff, for the supply and manufacture of Investigational Medicinal Products (IMPs) required for a clinical trial titled "Examining Antibiotics for Ulcerated Skin Cancer Surgical Excision". The industry category for this tender is medical equipment, pharmaceuticals, and personal care products. The contract, which has been awarded, involves specific tasks such as manufacturing and distributing flucloxacillin capsules and matching placebos. This procurement follows the limited procurement method, where the contract was negotiated without the publication of a notice, and Simbec-Orion has been identified as the sole supplier capable of meeting all the project requirements. The contract was signed on 1 January 2025, following a 10-day standstill period.

This tender presents significant opportunities for businesses specialising in the pharmaceutical industry, particularly those with expertise in clinical trial supplies, regulatory compliance, and Quality Assurance (QA) certification. Companies capable of handling the complex logistics of packaging, labelling, and meeting clinical trial regulatory requirements would find this contract highly beneficial. Such businesses would not only contribute to essential medical research but would also enhance their reputation and market presence by participating in high-stake government-funded projects like this one. The unique demands of this project highlight the need for specialised skills and capabilities, ensuring that only well-suited firms like Simbec-Orion, with comprehensive service offerings, can compete effectively.

## Notice

Cardiff and Vale University Health Board (CAVUHB) is undertaking a clinical trial entitled 'Examining Antibiotics for Ulcerated Skin Cancer Surgical Excision', funded by the National Institute for Health and Care Research (NIHR) Health Technology Assessment Programme (Ref: NIHR 160872). As part of this clinical trial, an Investigational Medicinal Product (IMP) needs to be manufactured and distributed.

### Lot Information

Lot 1

Supply and Manufacture of Investigational Medicinal Products (IMPs) for the Clinical Trial: "Examining Antibiotics for Ulcerated Skin Cancer Surgical Excision" Cardiff and Vale University Health Board (CAVUHB) is undertaking a clinical trial entitled 'Examining Antibiotics for Ulcerated Skin Cancer Surgical Excision', funded by the National Institute for Health and Care Research (NIHR) Health Technology Assessment Programme (Ref: NIHR 160872). As part of this clinical trial, an Investigational Medicinal Product (IMP) needs to be manufactured and distributed. The IMPs required are: -Flucloxacillin 2 x 500mg capsules, over encapsulated -A matching placebo of inert filler, over encapsulated to match flucloxacillin 2 x 500mg capsules. The successful supplier will be responsible for the manufacture, packaging, labelling, Quality Assurance (QA) certification, storage, shipment, and regulatory compliance (CTIMP regulations) associated with the trial's IMPs. After extensive market research and consultations with multiple suppliers, it has been concluded that only one supplier, Simbec-Orion, has the capability to fulfil the full scope of the contract requirements. This includes: -Over encapsulation of flucloxacillin and matching placebo -Packaging and labelling of the final product -Compliance with clinical trial regulations (CTIMP) -Storage and shipment logistics to participating NHS sites -QA certification and regulatory compliance for blinded clinical trials Simbec-Orion will also source the bulk IMP (4 lots of flucloxacillin, 1 lot of placebos), over encapsulate the product, and ensure all necessary documentation and quality assurance procedures are met. Simbec-Orion is uniquely positioned to meet the requirements of the clinical trial due to its established capabilities in the manufacture and regulatory compliance of Investigational Medicinal Products (IMPs). No other supplier was found to be able to offer the complete set of services required for this project.

### Procurement Information

The products involved are manufactured purely for the purpose of research. In addition, Simbec-Orion is positioned to meet the requirements of the clinical trial. No other supplier was found to be able to offer the complete set of services required for this project.

## Key Details

| Field | Value |
| --- | --- |
| Publication source | Find A Tender Service |
| Latest notice | https://www.find-tender.service.gov.uk/Notice/001841-2025 |
| Notice type | Award Notice |
| Procurement type | Standard |
| Procurement category | Goods |
| Procurement method | Limited |
| Procurement method details | Negotiated without publication of a contract notice |
| Tender suitability | Not specified |
| Awardee scale | SME |
| All stages | Award |

## Dates

| Field | Value |
| --- | --- |
| Publication date | 20 Jan 2025 |
| Submission deadline | Not specified |
| Future notice date | Not specified |
| Award date | 1 Jan 2025 |
| Contract period | Not specified |
| Recurrence | Not specified |

## Values

| Field | Value |
| --- | --- |
| Tender value | Not specified |
| Lots value | Not specified |
| Awards value | Not specified |
| Contracts value | £116,645 |

## Status

| Field | Value |
| --- | --- |
| Tender status | Complete |
| Lots status | Not specified |
| Awards status | Active |
| Contracts status | Active |

## Buyer

| Field | Value |
| --- | --- |
| Main buyer | NHS WALES SHARED SERVICES PARTNERSHIP (NWSSP) - PROCUREMENT SERVICES |
| Locality | CARDIFF |
| Post town | Cardiff |
| Postcode | CF14 4HH |
| Country | Wales |
| ITL 1 | TLL Wales |
| ITL 2 | TLL5 South East Wales |
| ITL 3 | TLL52 Cardiff and Vale of Glamorgan |
| Local authority | Cardiff |
| Electoral ward | Heath |
| Westminster constituency | Cardiff North |
| Delivery location | TLL22 Cardiff and Vale of Glamorgan |

## Supplier

| Field | Value |
| --- | --- |
| Number of suppliers | 1 |
| Supplier names | SIMBEC RESEARCH |

## CPV Codes

### Divisions

- 33 - Medical equipments, pharmaceuticals and personal care products

### Codes

- 33000000 - Medical equipments, pharmaceuticals and personal care products

## Release History

- 20 Jan 2025 at 12:02 - Award - Award Notice - https://www.find-tender.service.gov.uk/Notice/001841-2025

## Notice URLs

- http://nwssp.nhs.wales/ourservices/procurement-services/
- https://www.sell2wales.gov.wales/Search/Search_Switch.aspx?ID=147495
- https://www.sell2wales.gov.wales/search/Search_AuthProfile.aspx?ID=AA0221

## Provenance

This Markdown file is an alternate public rendering of the D3 Tenders contract record. The canonical page is https://d3tenders.com/contract/?ocid=ocds-h6vhtk-04d494. The underlying structured data is available as OCDS JSON at https://d3tenders.com/contract/ocds-h6vhtk-04d494.json.