---
title: "Supply of Plasmids and Synthetic DNA for Viral Vector Manufacture"
ocid: "ocds-h6vhtk-0586a2"
canonical_url: "https://d3tenders.com/contract/?ocid=ocds-h6vhtk-0586a2"
markdown_url: "https://d3tenders.com/contract/ocds-h6vhtk-0586a2.md"
json_url: "https://d3tenders.com/contract/ocds-h6vhtk-0586a2.json"
source: "Find A Tender Service"
current_stage: "Planning"
buyer: "NHS BLOOD AND TRANSPLANT"
published: "2025-08-13"
---

# Supply of Plasmids and Synthetic DNA for Viral Vector Manufacture

Buyer: NHS BLOOD AND TRANSPLANT  
Current stage: Planning  
OCID: ocds-h6vhtk-0586a2

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## Summary

The procurement process for the "Supply of Plasmids and Synthetic DNA for Viral Vector Manufacture" is currently in the planning stage, driven by NHS Blood and Transplant, a public authority central to the UK government. The procurement exercise is inviting further market engagement for the supply of nucleic acids, specifically plasmid DNA, synthetically and enzymatically produced DNA, for use in gene therapy vectors. NHSBT has issued this preliminary engagement to include synthetic options after initial engagement lacked them. Business stakeholders are urged to express their interest in this engagement by contacting the NHSBT by 12:00 hrs (GMT) on 12 September 2025, with the engagement set to take place via video calls later that month. This contract opportunity is valued at £8,640,000, indicating a significant investment in clinical products, with plans stretching from June 2026 until June 2034, highlighting a long-term collaboration potential.

This tender presents businesses within the biotechnology and pharmaceuticals industry an opportunity to expand into the gene therapy market by supplying crucial components used in both clinical trials and commercial production. Firms that possess capabilities in the production of high-grade plasmids and synthetic DNA, particularly those engaged in GMP (Good Manufacturing Practice) production or conducted R&D in nucleic acids, will find this tender particularly suited to their expertise. Moreover, the planned framework agreements facilitate ongoing partnerships, offering sustained growth and stability for businesses involved. The engagement process is an excellent entry point for suppliers to align with NHSBT's requirements, positioning themselves as key players in innovative therapeutic vectors development.

## Notice

As part of a preliminary market engagement exercise, NHS Blood & Transplant (NHSBT) are seeking to engage with suppliers of nucleic acids including plasmid DNA; synthetically produced DNA and/or enzymatically produced DNA. The intended use of the nucleic acids by NHSBT includes: a) the GMP grade production of gene therapy vectors such as lentiviral, adeno-associated viral vectors and novel gene therapy vectors, for clinical trials and commercial production where applicable; b) gene therapy vectors suitable for pre-clinical studies, such as toxicology and biodistribution studies and gene therapy vectors suitable for R&D purposes.

### Planning Information

NHSBT conducted initial market engagement for ' Supply of Viral Vector Plasmids', via issue of a PIN under the Procurement Contract Regulations (Notice Identifier: 2024/S 000-029545). NHSBT have since updated the requirement to include synthetically produced DNA and/or enzymatically produced DNA. Therefore NHSBT are looking to engage further with suppliers who may have been missed from the initial market engagement, due to synthetic plasmids not being included. If you are interested in taking part in the market engagement, please contact james.marshall2@nhsbt.nhs.uk by no later than 12:00 hrs (GMT) on 12/09/2025. Market engagement is likely to take place via video calls in September 2025. There is no guarantee that a formal procurement process will be launched as a result of this early market engagement exercise, nor that any contract(s) will be placed. No remuneration or compensation etc will be paid to organisations who take part in this early market engagement exercise. Suppliers should take part in this process only on the basis that they fully understand and accept this position.

## Key Details

| Field | Value |
| --- | --- |
| Publication source | Find A Tender Service |
| Latest notice | https://www.find-tender.service.gov.uk/Notice/048226-2025 |
| Notice type | UK2 - Preliminary Market Engagement Notice |
| Procurement type | Framework |
| Procurement category | Goods |
| Procurement method | Not Specified |
| Procurement method details | Not specified |
| Tender suitability | Not specified |
| Awardee scale | Not specified |
| All stages | Planning |

## Dates

| Field | Value |
| --- | --- |
| Publication date | 13 Aug 2025 |
| Submission deadline | Not specified |
| Future notice date | 8 Dec 2025 |
| Award date | Not specified |
| Contract period | 14 Jun 2026 - 14 Jun 2034 |
| Recurrence | Not specified |

## Values

| Field | Value |
| --- | --- |
| Tender value | £7,200,000 |
| Lots value | Not specified |
| Awards value | Not specified |
| Contracts value | Not specified |

## Status

| Field | Value |
| --- | --- |
| Tender status | Planning |
| Lots status | Planning |
| Awards status | Not specified |
| Contracts status | Not specified |

## Buyer

| Field | Value |
| --- | --- |
| Main buyer | NHS BLOOD AND TRANSPLANT |
| Locality | BRISTOL |
| Post town | Bristol |
| Postcode | BS34 7QH |
| Country | England |
| ITL 1 | TLK South West (England) |
| ITL 2 | TLK5 West of England |
| ITL 3 | TLK52 Bath & North East Somerset and South Gloucestershire |
| Local authority | South Gloucestershire |
| Electoral ward | Filton |
| Westminster constituency | Filton and Bradley Stoke |
| Delivery location | TLK11 Bristol, City of |

## CPV Codes

### Divisions

- 33 - Medical equipments, pharmaceuticals and personal care products

### Codes

- 33698000 - Clinical products

## Release History

- 13 Aug 2025 at 07:21 - Planning - UK2 - Preliminary Market Engagement Notice - https://www.find-tender.service.gov.uk/Notice/048226-2025

## Documents

- https://www.find-tender.service.gov.uk/Notice/048226-2025
  13th August 2025 - Preliminary market engagement notice on Find a Tender

## Notice URLs

- https://www.legislation.gov.uk/ukpga/2023/54/contents
- https://www.nhsbt.nhs.uk/

## Provenance

This Markdown file is an alternate public rendering of the D3 Tenders contract record. The canonical page is https://d3tenders.com/contract/?ocid=ocds-h6vhtk-0586a2. The underlying structured data is available as OCDS JSON at https://d3tenders.com/contract/ocds-h6vhtk-0586a2.json.