---
title: "high-throughput sequencing services"
ocid: "ocds-h6vhtk-058ffe"
canonical_url: "https://d3tenders.com/contract/?ocid=ocds-h6vhtk-058ffe"
markdown_url: "https://d3tenders.com/contract/ocds-h6vhtk-058ffe.md"
json_url: "https://d3tenders.com/contract/ocds-h6vhtk-058ffe.json"
source: "Find A Tender Service"
current_stage: "Award"
buyer: "CELL THERAPY CATAPULT LIMITED"
published: "2025-12-05"
---

# high-throughput sequencing services

Buyer: CELL THERAPY CATAPULT LIMITED  
Current stage: Award  
OCID: ocds-h6vhtk-058ffe

[View canonical contract page](https://d3tenders.com/contract/?ocid=ocds-h6vhtk-058ffe)  
[Download OCDS JSON](https://d3tenders.com/contract/ocds-h6vhtk-058ffe.json)

## Summary

Cell Therapy Catapult Limited, located in London, United Kingdom, has completed its procurement process to secure high-throughput sequencing services. This contract aims to accelerate the commercialization of innovation from research within the Cell and Gene Therapy industry. The procurement was conducted through an open, below-threshold competition, concluding with awards for several sequencing services, such as RNA and genome sequencing. The awarded contracts commenced in January 2026, following the most recent contract awards announced on 5th December 2025. This procurement falls under the research services category and focuses on advanced therapy medicinal products development.

These contracts offer significant growth opportunities for businesses involved in sequencing and analysis technologies. Given the diverse requirements, companies with a focus on bioinformatics, RNA sequencing, and genome analysis, especially SMEs, stand to benefit greatly from participating in such tenders. The procurement allows for collaboration over extended periods, offering a possibility of a three-year contract with yearly renewals. With projects covering bulk RNA, single-cell RNA, and genome sequencing, there is immense scope for innovative businesses to contribute to cutting-edge research, making this tender an attractive proposition for those looking to expand their footprint in the healthcare and biotechnology industries.

## Notice

The primary aim of this procurement is to secure a high-throughput sequencing service provider to perform sequencing services for the Cell and Gene Therapy (CGT) Catapult on a fee-per-service basis. This service will support the CGT Catapult's mission of accelerating the commercialization of innovation from research and overcoming technical barriers in advanced therapy medicinal product (ATMP) development. The selected provider's services will complement CGT Catapult's unique technical facilities and expertise at its London site. This procurement seeks comprehensive high-throughput sequencing services. These services will be utilized for deep process characterization, particularly for processes like stem cell differentiation and viral vector manufacturing. The required services include, but are not limited to: Lot 1 - High-throughput short-read sequencing of libraries generated by CGT Catapult (i.e., sequencing only) Lot 2 - Bulk RNA sequencing Lot 3 - Bulk small RNA sequencing Lot 4 - Single-cell RNA sequencing (scRNA-seq) of cryopreserved/fixed samples Lot 5 - AAV genome short-read sequencing Lot 6 - Sanger sequencing

### Lot Information

High-throughput short-read sequencing of libraries generated by CGT Catapult (i.e., sequencing-only)

For this service, the provider will receive pre-prepared library pools from CGT Catapult ready for sequencing. These libraries may originate from various sources and experimental designs, representing the final product of CGT Catapult's library preparation efforts. The service should include a Quality Control (QC) step to ascertain whether the provided library sample is considered suitable for downstream sequencing. This QC should evaluate factors such as the presence of adapter artifacts and confirm a minimum yield/concentration. The required throughput per run will vary based on project needs, but typical requirements for human cell-based applications often range from 20 to 30 million reads per sample for messenger RNA profiling and from 40 to 50 million reads per sample for total RNA profiling. Readouts other than gene expression may have other minimum read number requirements. Sequencing should be performed with flexibility for both single-read and paired-end sequencing modes, with read lengths up to 150 bp. The option for specifying read strandedness should also be available, as required by the experimental design. Typically, sample QC should be completed within 1-5 business days of receipt of the library pool(s). Sequencing run completion and raw data delivery are expected to be from 2 weeks to 3 months.

Renewal: The contract period is for a 1-year contract with the possibility to extend for 1 year and a further 1 year (1+1+1 years). The maximum total contract is 3 years.

Bulk RNA sequencing

This service will typically involve library preparation and sequencing from cell pellets or isolated RNA samples provided by CGT Catapult. These samples will be derived from various cell lines undergoing different processes. The sequencing throughput, read strandedness, and mode will be contingent on project needs. Additionally, the provider should offer tiered support for data analysis, ranging from raw data processing (e.g., demultiplexing, adapter trimming, read alignment, quantification of gene counts) to statistical analysis (e.g., differential gene expression analysis, clustering) and functional enrichment analysis (e.g., pathway enrichment analysis), contingent on project needs. Sample QC and library preparation typically take 3-14 business days. Sequencing run completion and raw data delivery are expected to be from 2 weeks to 3 months. Tiered data analysis can take 2 weeks to 2 months, depending on the complexity of the analysis.

Renewal: The contract period is for a 1-year contract with the possibility to extend for 1 year and a further 1 year (1+1+1 years). The maximum total contract is 3 years.

Bulk small RNA sequencing

For bulk small RNA sequencing, the provider will generally receive cell pellets, cell culture supernatant, or extracted RNA samples from CGT Catapult. These samples will be used to profile microRNAs and other small non-coding RNAs. The provider should also offer tiered support for data analysis, ranging from raw data processing to statistical analysis, including annotation to known microRNAs or other small RNA types (e.g., piRNAs) and de novo small RNA discovery, contingent on project needs. Sample QC and library preparation typically take 3-14 business days. Sequencing run completion and raw data delivery are expected to be from 2 weeks to 3 months. Tiered data analysis can take 2 weeks to 2 months, depending on the complexity of the analysis.

Renewal: The contract period is for a 1-year contract with the possibility to extend for 1 year and a further 1 year (1+1+1 years). The maximum total contract is 3 years.

Single-cell RNA sequencing (scRNA-seq) of cryopreserved/fixed samples

This service will involve library preparation and sequencing where cryopreserved or fixed cell samples will be provided by CGT Catapult. The throughput for single-cell sequencing should accommodate varying project sizes with regards to number of samples, number of profiled cells per sample, and number of reads to obtain per cell. Sample QC and library preparation typically take 3-14 business days. Sequencing run completion and raw data delivery are expected to be from 2 weeks to 3 months.

Renewal: The contract period is for a 1-year contract with the possibility to extend for 1 year and a further 1 year (1+1+1 years). The maximum total contract is 3 years.

AAV genome sequencing

This service will involve analysis of AAV samples (final product) to confirm packaged AAV genome sequence and detect any DNA impurities in the sample. Different AAV serotypes may be used. For a sequencing-only service, AAV genomes will be extracted and libraries generated at CGT Catapult and sent to the provider for downstream sequencing. For end-to-end QC analysis of AAV samples, CGT Catapult samples will be sent to the provider for library generation and QC. Long-read sequencing using PacBio instrumentation will be performed to assess AAV genome integrity, while short-read sequencing will be utilized to confirm sequence of AAV vectors and identify contaminants. Specific requirements for this AAV analysis will depend on project needs. Sample QC and library preparation typically take 3-14 business days. Sequencing run completion and raw data delivery are expected to be from 2 weeks to 3 months. Tiered data analysis can take 2 weeks to 2 months, depending on the complexity of the analysis.

Renewal: The contract period is for a 1-year contract with the possibility to extend for 1 year and a further 1 year (1+1+1 years). The maximum total contract is 3 years.

Sanger sequencing

This service is required for targeted sequencing applications, such as confirming effective gene knockout after CRISPR-Cas9 editing, validating the successful insertion of gene cassettes, or verifying specific point mutations. CGT Catapult will typically provide purified DNA samples (e.g., plasmid DNA, PCR amplicons) for this service. The provider should offer robust quality control to ensure sample suitability, followed by sequencing and primary data analysis, including trace visualization and base calling. The expected output is high-quality sequence reads for individual targets, enabling precise validation of genetic modifications. This service typically takes 1-5 business days from sample receipt.

Renewal: The contract period is for a 1-year contract with the possibility to extend for 1 year and a further 1 year (1+1+1 years). The maximum total contract is 3 years.

## Key Details

| Field | Value |
| --- | --- |
| Publication source | Find A Tender Service |
| Latest notice | https://www.find-tender.service.gov.uk/Notice/080291-2025 |
| Notice type | UK6 - Contract Award Notice |
| Procurement type | Standard |
| Procurement category | Services |
| Procurement method | Open |
| Procurement method details | Below threshold - open competition |
| Tender suitability | SME, VCSE |
| Awardee scale | Large, SME |
| All stages | Tender, Award |

## Dates

| Field | Value |
| --- | --- |
| Publication date | 5 Dec 2025 |
| Submission deadline | 12 Sep 2025 |
| Future notice date | Not specified |
| Award date | 5 Dec 2025 |
| Contract period | 7 Jan 2026 - 6 Jan 2027 |
| Recurrence | Not specified |

## Values

| Field | Value |
| --- | --- |
| Tender value | £132,000 |
| Lots value | £132,000 |
| Awards value | £144,717 |
| Contracts value | Not specified |

## Status

| Field | Value |
| --- | --- |
| Tender status | Complete |
| Lots status | Complete |
| Awards status | Active |
| Contracts status | Not specified |

## Buyer

| Field | Value |
| --- | --- |
| Main buyer | CELL THERAPY CATAPULT LIMITED |
| Locality | LONDON |
| Post town | South East London |
| Postcode | SE1 9RT |
| Country | England |
| ITL 1 | TLI London |
| ITL 2 | TLI4 Inner London - East |
| ITL 3 | TLI44 Lewisham and Southwark |
| Local authority | Southwark |
| Electoral ward | London Bridge & West Bermondsey |
| Westminster constituency | Bermondsey and Old Southwark |
| Delivery location | TLC North East (England), TLD North West (England), TLE Yorkshire and The Humber, TLF East Midlands (England), TLG West Midlands (England), TLH East (England), TLI London, TLJ South East (England), TLK South West (England) |

## Supplier

| Field | Value |
| --- | --- |
| Number of suppliers | 4 |
| Supplier names | BIOMARKER TECHNOLOGIES (BMK; EDINBURGH GENETICS; GENEWIZ; NOVOGENE (UK |

## CPV Codes

### Divisions

- 73 - Research and development services and related consultancy services

### Codes

- 73000000 - Research and development services and related consultancy services
- 73100000 - Research and experimental development services
- 73110000 - Research services

## Release History

- 5 Dec 2025 at 15:54 - Award - UK6 - Contract Award Notice - https://www.find-tender.service.gov.uk/Notice/080291-2025
- 29 Aug 2025 at 08:50 - Tender - UK4 - Tender Notice - https://www.find-tender.service.gov.uk/Notice/052281-2025

## Documents

- https://www.find-tender.service.gov.uk/Notice/080291-2025
  5th December 2025 - Contract award notice on Find a Tender
- https://www.find-tender.service.gov.uk/Notice/052281-2025
  29th August 2025 - Tender notice on Find a Tender

## Notice URLs

- http://eggenetics.com
- https://catapultcgtc.wax-live.com/S2C/DisplayModules/TradeModules/Negotiations/Opportunities/ListEvents.aspx?ApplicationInstanceID=27adc89e-0cb2-4b51-9bc1-34061f10156f
- https://catapultcgtc.wax-live.com/S2C/DisplayModules/TradeModules/Negotiations/Opportunities/ListEvents.aspx?ApplicationInstanceID=27adc89e-0cb2-4b51-9bc1-34061f10156fAccessdocumentsviatheabovelink
- https://www.genewiz.com/
- https://www.legislation.gov.uk/ukpga/2023/54/contents
- https://www.novogene.com/

## Provenance

This Markdown file is an alternate public rendering of the D3 Tenders contract record. The canonical page is https://d3tenders.com/contract/?ocid=ocds-h6vhtk-058ffe. The underlying structured data is available as OCDS JSON at https://d3tenders.com/contract/ocds-h6vhtk-058ffe.json.