--- title: "In Service Evaluation into Newborn Screening for Spinal Muscular Atrophy and Severe Combined Immunodeficiency (SMA and SCID)" ocid: "ocds-h6vhtk-06cc9d" canonical_url: "https://d3tenders.com/contract/?ocid=ocds-h6vhtk-06cc9d" markdown_url: "https://d3tenders.com/contract/ocds-h6vhtk-06cc9d.md" json_url: "https://d3tenders.com/contract/ocds-h6vhtk-06cc9d.json" source: "Find A Tender Service" current_stage: "Planning" buyer: "DEPARTMENT OF HEALTH & SOCIAL CARE" published: "2026-07-16" --- # In Service Evaluation into Newborn Screening for Spinal Muscular Atrophy and Severe Combined Immunodeficiency (SMA and SCID) Buyer: DEPARTMENT OF HEALTH & SOCIAL CARE Current stage: Planning OCID: ocds-h6vhtk-06cc9d [View canonical contract page](https://d3tenders.com/contract/?ocid=ocds-h6vhtk-06cc9d) [Download OCDS JSON](https://d3tenders.com/contract/ocds-h6vhtk-06cc9d.json) ## Summary The Department of Health & Social Care, located in London, is seeking financial collaboration from organisations within the voluntary, community, social enterprise, and private sectors. The procurement process is in the planning stage for an "In Service Evaluation into Newborn Screening for Spinal Muscular Atrophy and Severe Combined Immunodeficiency (SMA and SCID)" across England. This initiative aims to broaden the programme's coverage from seven to thirteen laboratories. Interested parties are invited to express their interest by 7th August 2026. The procurement falls under the UK central government's public authority, seeking an extension of the newborn screening programme, with operational capacity for additional labs expected by Q3 of 2027. This process is preliminary market engagement to find strategic collaborators and involves no public contract awarding under the Procurement Act 2023. This tender presents significant opportunities for businesses involved in health services, medical analysis, research and development, and diagnostic services. Organisations capable of providing financial support for expanding laboratory infrastructure, expertise, and research will find this an advantageous opportunity to contribute to a life-saving public health initiative. Companies specialising in medical laboratory services, pharmacy services, and medical specialist services are particularly well-suited to engage in this collaboration, potentially establishing themselves as key players in the public health landscape while supporting the UK's national healthcare objectives. ## Notice 1. INTRODUCTION 1.1. This general information notice is published to provide information about how the Department of Health and Social Care (DHSC) will be engaging with interested parties to find one or more strategic collaborator/donor. 1.2. DHSC is seeking expressions of interest from organisations in the voluntary, community, social enterprise (VCSE) and private sectors to collaborate in support of both the capital and revenue commitments to enable the extension at pace of the existing In Service Evaluation (ISE) into newborn Spinal Muscular Atrophy (SMA) screening in England, which will also include evaluating screening for Severe Combined Immunodeficiency (SCID). 1.3. The focus of this collaboration is the financial contribution required for the set up and running of an additional 6 newborn screening centres over a two year period (with the first of the additional centres looking to be operational by Q3 of 2027) 1.4. This is not a public procurement or sponsorship opportunity and will not result in the award of a "public contract" (within the meaning of the Procurement Act 2023). DHSC is specifically looking for financial contributions and wishes to hear from interested parties who can help us to: * Extend the screening and laboratory testing process to enable all babies in England to receive the offer of screening. * Help with the early identification of SMA in newborns by extending the evaluation of SMA / SCID screening to an additional 6 labs. Engagement process and deadline 1.5. Full details of the requirement can be found within section 3 of this document. Those wishing to participate in the engagement process should register their interest by completing and submitting the questionnaire at the following link: https://forms.office.com/e/2FwiSsY8ib 1.6. The closing date for responses is on: 7th August at 23.59 pm. We reserve the right not to accept responses after this time. 1.7. We will be using a fair and non-discriminatory evaluation method to select interested parties to enter into discussions regarding a potential collaboration/donation agreement following the close of the early market engagement process. 1.8. DHSC will carry out due diligence relating to your organisation's financial position, track record and other information it reasonably deems necessary or appropriate to satisfy itself as to the accuracy and adequacy of the responses received. This may involve the use of a range of tools and sources including, but not limited to, data analytics and artificial intelligence (AI). 1.9. DHSC intends to select organisations to collaborate with, but it reserves its right to select fewer organisations and/or not form a collaboration/donation agreement. 1.10. The questionnaire contains 4 questions for interested parties to answer. Each question refers to a key aspect of the requirements set out in Appendix 1. Each question will be scored on a scale of 0-4 using the scoring criteria set out below: Score Criteria for awarding score 0 Failure to understand requirements and provides no confidence that the requirement will be met. 1 The response meets some elements of the requirement but falls short in many significant areas. There are strong reservations because the response shows: Some misunderstandings of the requirements and insufficient supporting information is provided. It provides low confidence that the requirements will be met. 2 The response broadly meets what is expected for the requirements, but there are some areas of concern. The response shows: A basic understanding of the requirements and a minimum level of supporting information provided. It provides reasonable confidence that the requirements will be met. 3 The response meets the requirements in all material respects, with no or few areas of concern. The response shows: A good understanding of the requirements and a good level of supporting information provided. It provides good degree confidence that the requirements will be met. 4 The response exceeds many aspects of the requirements. There are no areas of concern. The response shows: A very good understanding of the requirements and very good level of supporting information provided. It provides a high degree of confidence that the requirements will be met. 2. BACKGROUND Spinal Muscular Atrophy (SMA) in newborns is a severe genetic condition that affects the motor nerves in the spinal cord. This nerve damage leads to progressive muscle weakness, severely impacting a baby's ability to move, swallow, and breathe. It is a leading genetic cause of infant mortality. SMA is caused by a missing or faulty gene called SMN1. For a baby to be born with SMA, both biological parents must be carriers of this mutated gene and pass it on to their child. Carriers typically show no symptoms themselves. In many countries, SMA is now included in routine newborn screening programs (often part of the newborn blood spot or "heel prick" test) to allow for early diagnosis before symptoms even begin. Diagnostic confirmation involves a simple genetic blood test. Severe combined immunodeficiency (SCID) is the name given to a group of rare, inherited disorders that cause major abnormalities of the immune system. They form part of a larger group of conditions known as primary immunodeficiencies. The immune system abnormalities in SCID lead to greatly increased risks of infection and other complications that are life-threatening. Affected infants become unwell within the first few months of life, and before modern medication and treatments were available, most affected babies did not survive beyond their first year. At present, DHSC via NHS England are currently funding the implementation of "in-service evaluation" SMA screening in seven of England's thirteen newborn blood spot screening laboratories, (screening 410,000 babies per year). All of these seven laboratories possess the infrastructure, workforce expertise and operational capability required. These laboratories are also currently delivering Severe Combined Immunodeficiency (SCID) screening using the same testing platform and processes. To move at pace and lift screening capacity to all 13 screening laboratories which would provide coverage to the whole of England (additional 185,000 babies per year) further financial support is required. ### Planning Information We are seeking interested parties who are willing to provide : • Financial support to enable the extension of the existing SMA and SCID programmes, increasing national coverage from seven to thirteen laboratories. (this is expected to be in the region of £5.5 M for the 2 year period). • Financial support to meet capital investment and revenue costs associated with establishing and operating the six additional laboratories over a two-year period • Financial investment to amplify and extend existing screening research, generating the robust evidence required to inform the review and support any future recommendations. Should the programme be recommended for implementation, funding is anticipated to be secured through the Spending Review process. • Financial support for project team funding to optimise implementation of the extension In return, DHSC may: • Seek opportunities to secure Minister promotion of the contribution made by all collaborating organisations • Seek opportunities once funding is secured to move at pace to implement the role out via NHS England of further screening and laboratory testing to widen the newborn screening programme • Seek to build data and evidence from the existing 7 and collaborator funded 6 screening laboratories • Enable screening laboratories to provide additional expertise and evidence to support ongoing funding for the likely onward continuation of the programme via the spending review process and UKNSC recommendations Please respond using the following link: https://forms.office.com/e/2FwiSsY8ib All responses must be submitted by 7th August 2026 at 23:59pm. We reserve the right not to accept responses after this time. Press release: Every baby in England to get life-saving genetic test from birth (https://www.gov.uk/government/news/every-baby-in-england-to-get-life-saving-genetic-test-from-birth) ## Key Details | Field | Value | | --- | --- | | Publication source | Find A Tender Service | | Latest notice | https://www.find-tender.service.gov.uk/Notice/067135-2026 | | Notice type | UK2 - Preliminary Market Engagement Notice | | Procurement type | Standard | | Procurement category | Goods | | Procurement method | Not Specified | | Procurement method details | Not specified | | Tender suitability | Not specified | | Awardee scale | Not specified | | All stages | Planning | ## Dates | Field | Value | | --- | --- | | Publication date | 16 Jul 2026 | | Submission deadline | Not specified | | Future notice date | 7 Aug 2026 | | Award date | Not specified | | Contract period | 9 Aug 2026 - 2 Nov 2029 | | Recurrence | Not specified | ## Values | Field | Value | | --- | --- | | Tender value | Not specified | | Lots value | Not specified | | Awards value | Not specified | | Contracts value | Not specified | ## Status | Field | Value | | --- | --- | | Tender status | Planning | | Lots status | Planning | | Awards status | Not specified | | Contracts status | Not specified | ## Buyer | Field | Value | | --- | --- | | Main buyer | DEPARTMENT OF HEALTH & SOCIAL CARE | | Locality | LONDON | | Post town | South West London | | Postcode | SW1H 0EU | | Country | England | | ITL 1 | TLI London | | ITL 2 | TLI3 Inner London - West | | ITL 3 | TLI35 Westminster and City of London | | Local authority | Westminster | | Electoral ward | St James's | | Westminster constituency | Cities of London and Westminster | | Delivery location | Not specified | ## CPV Codes ### Divisions - 33 - Medical equipments, pharmaceuticals and personal care products - 73 - Research and development services and related consultancy services - 85 - Health and social work services ### Codes - 33694000 - Diagnostic agents - 73100000 - Research and experimental development services - 73110000 - Research services - 85100000 - Health services - 85121200 - Medical specialist services - 85140000 - Miscellaneous health services - 85145000 - Services provided by medical laboratories - 85148000 - Medical analysis services - 85149000 - Pharmacy services ## Release History - 16 Jul 2026 at 10:04 - PlanningUpdate - UK2 - Preliminary Market Engagement Notice - https://www.find-tender.service.gov.uk/Notice/067135-2026 - 16 Jul 2026 at 09:55 - Planning - UK2 - Preliminary Market Engagement Notice - https://www.find-tender.service.gov.uk/Notice/067126-2026 ## Documents - https://www.find-tender.service.gov.uk/Notice/067135-2026 16th July 2026 - Preliminary market engagement notice on Find a Tender - https://www.find-tender.service.gov.uk/Notice/067126-2026 16th July 2026 - Preliminary market engagement notice on Find a Tender ## Notice URLs - https://forms.office.com/e/2FwiSsY8ib - https://www.gov.uk/government/news/every-baby-in-england-to-get-life-saving-genetic-test-from-birth - https://www.gov.uk/government/organisations/department-of-health-and-social-care - https://www.legislation.gov.uk/ukpga/2023/54/contents ## Provenance This Markdown file is an alternate public rendering of the D3 Tenders contract record. The canonical page is https://d3tenders.com/contract/?ocid=ocds-h6vhtk-06cc9d. The underlying structured data is available as OCDS JSON at https://d3tenders.com/contract/ocds-h6vhtk-06cc9d.json.