---
title: "Seahorse XF Pro analyser"
ocid: "ocds-r6ebe6-0000757767"
canonical_url: "https://d3tenders.com/contract/?ocid=ocds-r6ebe6-0000757767"
markdown_url: "https://d3tenders.com/contract/ocds-r6ebe6-0000757767.md"
json_url: "https://d3tenders.com/contract/ocds-r6ebe6-0000757767.json"
source: "Public Contracts Scotland"
current_stage: "Award"
buyer: "UNIVERSITY OF EDINBURGH"
published: "2024-02-14"
---

# Seahorse XF Pro analyser

Buyer: UNIVERSITY OF EDINBURGH  
Current stage: Award  
OCID: ocds-r6ebe6-0000757767

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## Summary

The University of Edinburgh awarded a contract for a Seahorse XF Pro analyser to Agilent Technologies LDA UK Ltd. The procurement process was initiated as a tender and completed through a limited procurement method without prior publication of a call for competition. The equipment will allow real-time metabolic analysis of living cells and tissue explants in cardiovascular research, with a contract value of £194,806.88 signed on 8th February 2024. The University of Edinburgh, located in Edinburgh, UK, is a buyer in the Education industry category.

This tender for the Seahorse XF Pro analyser presents business growth opportunities for suppliers of advanced scientific equipment in the goods category. Companies offering unique, patented technologies for metabolic research in university settings would be well-suited to compete for similar tenders. The awarded contract signifies successful innovation and research advancement within the University of Edinburgh's Centre for Cardiovascular Science, demonstrating the potential for collaborations to drive future advancements in the field of metabolism research.

## Notice

The Centre for Cardiovascular Science (CVS) is part of the new Institute of Neuroscience and Cardiovascular Research (INCR). CVS comprises ~200 researchers encompassing a wide range of cardiovascular research split into four main themes (Metabolism, Obesity and Diabetes; Coronary and Valvular Heart Disease; Hypertension and Renal; Cardiometabolic Imaging). The equipment will allow high sensitivity measurement of real-time respiration in immortalised and primary cells and in tissue explants in several species.

### Lot Information

Lot 1

The Centre for Cardiovascular Science (CVS) is part of the new Institute of Neuroscience and Cardiovascular Research (INCR). CVS comprises ~200 researchers encompassing a wide range of cardiovascular research split into four main themes (Metabolism, Obesity and Diabetes; Coronary and Valvular Heart Disease; Hypertension and Renal; Cardiometabolic Imaging). Centre for Cardiovascular Science (CVS) requests an Agilent Seahorse XFe24 analyser and software for high throughput real-time metabolic analysis of living cells and tissue explants. The instrument will add easy-to-use capability for metabolic measurements in living cells to better understand cellular metabolism. The replacement XFe24 machine will support the requirements of the centre to deliver world-leading research in the field of metabolism. The replacement XFe24 will allow high sensitivity measurement of real-time respiration in immortalised and primary cells and in tissue explants in several species.

### Procurement Information

Seahorse XF instruments are the only ones that can simultaneously measures oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) of living cells, and do so with unrivalled speed and requiring less material, even than other systems that solely measure OCR. Using these measurements, glycolytic Proton Efflux Rate (PER) is easily calculated as an accurate measurement of glycolysis rates in real time. This measurement technology is covered by US patent # 7,276,351 meaning that no other company can offer this capability. The XFe24 Seahorse is the only commercially available instrument for scientific research that simultaneously measures the two major energy-producing pathways of the cell, mitochondrial respiration and glycolysis. The requested instrument is unique in its offerings and ability to perform measurements in living cells without using destructive methods, thus preserving cellular integrity, and allowing researchers to follow cell fate over time. The XFe24 allows simultaneous analysis of a plate containing 24 wells - and has the ability to study 3D models (e.g. islets, adipose cells and tissue explants) which is crucial for several groups in CVS. Four compounds can be injected sequentially into each of the 24 wells during measurement of cellular respiration (oxygen consumption and extracellular acidification) to determine cellular responses in real time. Unique technical features not found in any other instruments Instrument creates transient microchamber, makes optical measurements, and performs compound injections. Temperature controlled measurement chamber is maintained at 37degC +- 0.5degC; alternative temperatures supported. XFe analyzers are also supported to for analysis in a hypoxic chamber. Seahorse XF instruments are the only ones that can simultaneously measures oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) of living cells, and do so with unrivalled speed and requiring less material, even than other systems that solely measure OCR. The precision-molded enclosures on Agilent Seahorse XFe have specialty coatings and gaskets to shield the electronics and sample from ambient light, as well as block radiated and emitted electromagnetic interference

## Key Details

| Field | Value |
| --- | --- |
| Publication source | Public Contracts Scotland |
| Latest notice | https://www.publiccontractsscotland.gov.uk/search/show/search_view.aspx?ID=FEB498779 |
| Notice type | PCS Notice - Website Contract Award Notice |
| Procurement type | Standard |
| Procurement category | Goods |
| Procurement method | Limited |
| Procurement method details | Award procedure without prior publication of a call for competition |
| Tender suitability | Not specified |
| Awardee scale | Large |
| All stages | Award |

## Dates

| Field | Value |
| --- | --- |
| Publication date | 14 Feb 2024 |
| Submission deadline | Not specified |
| Future notice date | Not specified |
| Award date | 8 Feb 2024 |
| Contract period | Not specified |
| Recurrence | Not specified |

## Values

| Field | Value |
| --- | --- |
| Tender value | Not specified |
| Lots value | Not specified |
| Awards value | Not specified |
| Contracts value | £194,806 |

## Status

| Field | Value |
| --- | --- |
| Tender status | Complete |
| Lots status | Complete |
| Awards status | Not specified |
| Contracts status | Active |

## Buyer

| Field | Value |
| --- | --- |
| Main buyer | UNIVERSITY OF EDINBURGH |
| Locality | EDINBURGH |
| Post town | Edinburgh |
| Postcode | EH1 1HT |
| Country | Scotland |
| ITL 1 | TLM Scotland |
| ITL 2 | TLM1 East Central Scotland |
| ITL 3 | TLM13 City of Edinburgh |
| Local authority | City of Edinburgh |
| Electoral ward | City Centre |
| Westminster constituency | Edinburgh East and Musselburgh |
| Delivery location | TLM75 City of Edinburgh |

## Supplier

| Field | Value |
| --- | --- |
| Number of suppliers | 1 |
| Supplier names | AGILENT TECHNOLOGIES |

## CPV Codes

### Divisions

- 38 - Laboratory, optical and precision equipments (excl. glasses)

### Codes

- 38434000 - Analysers

## Release History

- 14 Feb 2024 at 00:00 - Award - PCS Notice - Website Contract Award Notice - https://www.publiccontractsscotland.gov.uk/search/show/search_view.aspx?ID=FEB498779

## Documents

- https://www.publiccontractsscotland.gov.uk/search/show/search_view.aspx?ID=FEB498779
  Seahorse XF Pro analyser - The Centre for Cardiovascular Science (CVS) is part of the new Institute of Neuroscience and Cardiovascular Research (INCR). CVS comprises ~200 researchers encompassing a wide range of cardiovascular research split into four main themes (Metabolism, Obesity and Diabetes; Coronary and Valvular Heart Disease; Hypertension and Renal; Cardiometabolic Imaging). The equipment will allow high sensitivity measurement of real-time respiration in immortalised and primary cells and in tissue explants in several species.

## Notice URLs

- http://
- https://api.publiccontractsscotland.gov.uk/v1/Notice?id=ocds-r6ebe6-0000757767
- https://www.ed.ac.uk

## Provenance

This Markdown file is an alternate public rendering of the D3 Tenders contract record. The canonical page is https://d3tenders.com/contract/?ocid=ocds-r6ebe6-0000757767. The underlying structured data is available as OCDS JSON at https://d3tenders.com/contract/ocds-r6ebe6-0000757767.json.
