Award

Proton range verification detectors

THE CHRISTIE NHS FOUNDATION TRUST

This public procurement record has 2 releases in its history.

Award

01 Jun 2022 at 14:01

Tender

21 Jan 2022 at 14:15

Summary of the contracting process

The Christie NHS Foundation Trust is initiating a public procurement process for "Proton range verification detectors" aimed at enhancing proton beam therapy by addressing range uncertainty issues. This tender falls under the classification of goods, specifically detection apparatus, with an estimated value of £130,000. The procurement method is an open procedure, and the tender period concludes on 24 February 2022, with a contract period ending on 31 December 2022. The procurement is based in Manchester, UK, and seeks innovative solutions to improve the accuracy of proton therapy treatments.

This tender presents significant opportunities for businesses specialising in medical technology and detection apparatus, particularly those focused on advanced imaging systems or radiation detection. Companies with expertise in developing high-resolution scintillator detectors, particularly LaBr3 scintillators as specified, would be well-positioned to compete. The successful bidder will contribute to a vital healthcare enhancement, potentially leading to further collaboration with NHS organisations and expanding their footprint in the public health sector.

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Notice Title

Proton range verification detectors

Notice Description

The PRECISE proton therapy research group at the University of Manchester and the Christie NHS Foundation Trust is developing a system to verify range during proton beam therapy treatments. Range uncertainty is arguably one of the biggest challenges in proton therapy. Range uncertainty arises from a number of sources: imaging, dosimetry, stopping powers, however, the largest uncertainty is always the patient. Patient setup, highly heterogeneous tissue, implants, or bone/tissue interfaces as well as anatomical changes during treatment can all influence proton range and thus, treatment outcomes. The full potential of proton beam therapy, particularly when there are organs-at-risk in the vicinity of the tumour, cannot be exploited unless these uncertainties are reduced or mitigated. One possible method of determining proton range is through the detection of the prompt gamma-rays that are emitted naturally during therapy. It has been shown experimentally that the maximum intensity of these prompt gamma rays correlates well with the Bragg peak and end-of-range. By detecting these prompt gamma-rays and determining their origin the proton beam range could be established. The system being developed is based on an array of scintillator detectors coupled with an image reconstruction algorithm based on gamma-ray coincidences. The detectors of choice are LaBr3 scintillators which exhibit good energy and timing resolution for the detection of the high energy gamma-rays emitted. The typical gamma-ray energy range of interest is 2 - 8 MeV so large crystal, 38.1 mm (1.5") diameter and 50.8 mm (2") long, detectors are required in order to obtain full energy photo peaks. As the reconstruction algorithm utilises gamma-ray coincidences, the detectors need to have an energy resolution of 3.5% or less at 662 keV and a coincidence resolving time of 0.5 ns or less. Ideally we are also looking for the detectors to have an anode pulse rise time of 0.8 ns or less and an electron transit time of 16 ns or less.

Lot Information

Lot 1

The PRECISE proton therapy research group at the University of Manchester and the Christie NHS Foundation Trust is developing a system to verify range during proton beam therapy treatments. Range uncertainty is arguably one of the biggest challenges in proton therapy. Range uncertainty arises from a number of sources: imaging, dosimetry, stopping powers, however, the largest uncertainty is always the patient. Patient setup, highly heterogeneous tissue, implants, or bone/tissue interfaces as well as anatomical changes during treatment can all influence proton range and thus, treatment outcomes. The full potential of proton beam therapy, particularly when there are organs-at-risk in the vicinity of the tumour, cannot be exploited unless these uncertainties are reduced or mitigated. One possible method of determining proton range is through the detection of the prompt gamma-rays that are emitted naturally during therapy. It has been shown experimentally that the maximum intensity of these prompt gamma rays correlates well with the Bragg peak and end-of-range. By detecting these prompt gamma-rays and determining their origin the proton beam range could be established. The system being developed is based on an array of scintillator detectors coupled with an image reconstruction algorithm based on gamma-ray coincidences. The detectors of choice are LaBr3 scintillators which exhibit good energy and timing resolution for the detection of the high energy gamma-rays emitted. The typical gamma-ray energy range of interest is 2 - 8 MeV so large crystal, 38.1 mm (1.5") diameter and 50.8 mm (2") long, detectors are required in order to obtain full energy photo peaks. As the reconstruction algorithm utilises gamma-ray coincidences, the detectors need to have an energy resolution of 3.5% or less at 662 keV and a coincidence resolving time of 0.5 ns or less. Ideally we are also looking for the detectors to have an anode pulse rise time of 0.8 ns or less and an electron transit time of 16 ns or less.

Publication & Lifecycle

Open Contracting ID
ocds-h6vhtk-030de2
Publication Source
Find A Tender Service
Latest Notice
https://www.find-tender.service.gov.uk/Notice/015374-2022
Current Stage
Award
All Stages
Tender, Award

Procurement Classification

Notice Type
Tender Notice
Procurement Type
Standard
Procurement Category
Goods
Procurement Method
Open
Procurement Method Details
Open procedure
Tender Suitability
Not specified
Awardee Scale
SME

Common Procurement Vocabulary (CPV)

CPV Divisions

38 - Laboratory, optical and precision equipments (excl. glasses)


CPV Codes

38431000 - Detection apparatus

Notice Value(s)

Tender Value
£130,000 £100K-£500K
Lots Value
Not specified
Awards Value
Not specified
Contracts Value
£120,290 £100K-£500K

Notice Dates

Publication Date
1 Jun 20223 years ago
Submission Deadline
24 Feb 2022Expired
Future Notice Date
Not specified
Award Date
23 May 20223 years ago
Contract Period
Not specified - Not specified
Recurrence
Not specified

Notice Status

Tender Status
Complete
Lots Status
Cancelled
Awards Status
Active
Contracts Status
Active

Contracting Authority (Buyer)

Main Buyer
THE CHRISTIE NHS FOUNDATION TRUST
Contact Name
Mr Chris Robson
Contact Email
christopher.robson4@nhs.net
Contact Phone
+44 1614468531

Buyer Location

Locality
MANCHESTER
Postcode
M20 4BX
Post Town
Manchester
Country
England

Major Region (ITL 1)
TLD North West (England)
Basic Region (ITL 2)
TLD3 Greater Manchester
Small Region (ITL 3)
TLD33 Manchester
Delivery Location
TLD3 Greater Manchester

Local Authority
Manchester
Electoral Ward
Withington
Westminster Constituency
Manchester Withington

Supplier Information

Number of Suppliers
1
Supplier Name

MI-NET TECHNOLOGY LTT

Open Contracting Data Standard (OCDS)

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