Producer Cell Line for GMP Viral Vector Packaging

Notice Information

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Notice Title

Producer Cell Line for GMP Viral Vector Packaging

Notice Description

The Clinical Biotechnology Centre (CBC) has recently validated a GMP-compliant recombinant adeno-associated viral vector (rAAV) manufacturing platform process to support UK academic clients in transitioning their gene therapy programmes from research into human clinical trials. The work took over four years of intensive effort, including initial process development, iterative process optimisation and scale-up to ensure suitability for GMP technology transfer. Critical starting and raw materials were selected and approved for use on the platform, as well as determining the optimal process parameters to ensure consistent performance. The validated platform process is now installed within the CBC's GMP clean room viral vector manufacturing suites. As rAAV manufacturing is inherently complex, technically demanding, and highly sensitive to changes in process conditions, any modification to the validated platform carries considerable risk to the quality of the products being manufactured. Even minor changes could have a significant impact to disrupt platform performance that would require months of expensive re-optimisation and re-validation activities, which would present unacceptable operational and business risks.

Procurement Information

CBC's validated GMP AAV platform being built and validated around VPC2.0 and continuity required to avoid disproportionate re-validation, delay, cost and operational risk. Only Thermo Fisher is able to grant the required rights and support for these specific cell lines, and no reasonable alternative exists without disproportionate consequences.

Notice Details

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Publication & Lifecycle

Open Contracting ID: ocds-h6vhtk-0680f1
Publication Source: Find A Tender Service
Latest Notice: https://www.find-tender.service.gov.uk/Notice/039802-2026
Current Stage: Award
All Stages: Award

Procurement Classification

Notice Type: UK6 - Contract Award Notice
Procurement Type: Standard
Procurement Category: Services
Procurement Method: Direct
Procurement Method Details: Direct award
Tender Suitability: SME
Awardee Scale: Large

Common Procurement Vocabulary (CPV)

CPV Divisions: 85 - Health and social work services
CPV Codes: 85100000 - Health services

Notice Value(s)

Tender Value: Not specified
Lots Value: Not specified
Awards Value: £180,000 £100K-£500K
Contracts Value: Not specified

Notice Dates

Publication Date: 30 Apr 20261 months ago
Submission Deadline: Not specified
Future Notice Date: Not specified
Award Date: 13 Apr 20262 months ago
Contract Period: 21 May 2026 - 31 Mar 2033 Over 5 years
Recurrence: Not specified

Notice Status

Tender Status: Complete
Lots Status: Complete
Awards Status: Pending
Contracts Status: Not Specified

Buyer & Supplier

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Contracting Authority (Buyer)

Main Buyer: NHS BLOOD AND TRANSPLANT
Contact Name: Available with D3 Tenders Premium →
Contact Email: Available with D3 Tenders Premium →
Contact Phone: Available with D3 Tenders Premium →

Buyer Location

Locality: BRISTOL
Postcode: BS34 7QH
Post Town: Bristol
Country: England
Major Region (ITL 1): TLK South West (England)
Basic Region (ITL 2): TLK5 West of England
Small Region (ITL 3): TLK52 Bath & North East Somerset and South Gloucestershire
Delivery Location: Not specified
Local Authority: South Gloucestershire
Electoral Ward: Filton
Westminster Constituency: Filton and Bradley Stoke

Supplier Information

Number of Suppliers: 1
Supplier Name: THERMO FISHER SCIENTIFIC

Further Information

Notice Documents

https://www.find-tender.service.gov.uk/Notice/039802-2026
30th April 2026 - Contract award notice on Find a Tender
https://www.find-tender.service.gov.uk/Notice/033233-2026
13th April 2026 - Transparency notice on Find a Tender

Notice URLs

Open Contracting Data Standard (OCDS)

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JSON Markdown

The Open Contracting Data Standard (OCDS) is a framework designed to increase transparency and access to public procurement data in the public sector. It is widely used by governments and organisations worldwide to report on procurement processes and contracts.

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