Notice Information
Notice Title
Provision of project-specific sequencing services
Notice Description
Profiling of 360 FFPE samples using Illumina TruSeq RNA Exome with claraT reporting & DDIR evaluation
Lot Information
Lot 1
RNA Sequencing Services in support of the CRUK funded GO2PRECISE study, which aims to analyse the biological features of >300 gastroesophageal cancer specimens from patients treated with chemotherapy in the UK wide GO2 clinical trial to define the biological features that determine beneficial responses to chemotherapy. This data will be used to develop a predictive biomarker test to optimise the effectiveness and tolerability of chemotherapy and targeted anti-cancer treatments for gastroesophageal cancer.
Procurement Information
The CRUK funded GO2PRECISE study aims to analyse the biological features of >300 gastroesophageal cancer specimens form patients treated with chemotherapy in the UK wide GO2 clinical trial to define the biological features that determine beneficial responses to chemotherapy. This data will be used to develop a predictive biomarker test to optimise the effectiveness and tolerability of chemotherapy and targeted anti-cancer treatments for gastroesophageal cancer. The Almac RNA Exome proprietary bioinformatics pipeline claraT is a unique software-driven solution, classifying biologically relevant gene expression signatures into a comprehensive easy-to-interpret report. It is optimised for the use of clinical tumour biopsies. The breadth of the biological analysis performed comprising, 62 unique gene expression signatures, 60 single gene drug targets and 4,000 single genes relevant to the cancer biology , together with its' suitability for diagnostic material and delivery to CLIA/GLP complaint protocols make this a uniquely valuable and cost plus time efficient product for delivery of the aims of the CRUK funded GO2PRECISE study. A single small biopsy only is available from each patient, and these specimens from a clinical trial are very difficult to obtain, extremely valuable and sufficient only for a single analysis. For the success of the project it is crucial that the biological analysis performed has a high technical success rate and provides the largest possible amount of biological information. We have performed preliminary analysis in a pilot which confirms the utility of this analytical approach.
Notice Details
Publication & Lifecycle
- Open Contracting ID
- ocds-r6ebe6-0000621417
- Publication Source
- Public Contracts Scotland
- Latest Notice
- https://www.publiccontractsscotland.gov.uk/search/show/search_view.aspx?ID=JUN387322
- Current Stage
- Award
- All Stages
- Award
Procurement Classification
- Notice Type
- OJEU - F3 - Contract Award Notice
- Procurement Type
- Standard
- Procurement Category
- Services
- Procurement Method
- Limited
- Procurement Method Details
- Award procedure without prior publication of a call for competition
- Tender Suitability
- Not specified
- Awardee Scale
- Large
Common Procurement Vocabulary (CPV)
- CPV Divisions
73 - Research and development services and related consultancy services
-
- CPV Codes
73110000 - Research services
Notice Value(s)
- Tender Value
- Not specified
- Lots Value
- Not specified
- Awards Value
- Not specified
- Contracts Value
- £273,000 £100K-£500K
Notice Dates
- Publication Date
- 28 May 20205 years ago
- Submission Deadline
- Not specified
- Future Notice Date
- Not specified
- Award Date
- 27 Mar 20205 years ago
- Contract Period
- Not specified - Not specified
- Recurrence
- Not specified
Notice Status
- Tender Status
- Complete
- Lots Status
- Complete
- Awards Status
- Not Specified
- Contracts Status
- Active
Buyer & Supplier
Contracting Authority (Buyer)
- Main Buyer
- UNIVERSITY OF DUNDEE
- Contact Name
- Becky Myles
- Contact Email
- b.myles@dundee.ac.uk
- Contact Phone
- +44 1382386811
Buyer Location
- Locality
- DUNDEE
- Postcode
- DD1 4HN
- Post Town
- Dundee
- Country
- Scotland
-
- Major Region (ITL 1)
- TLM Scotland
- Basic Region (ITL 2)
- TLM0 Eastern Scotland
- Small Region (ITL 3)
- TLM03 Angus and Dundee City
- Delivery Location
- TLN06 Belfast
-
- Local Authority
- Dundee City
- Electoral Ward
- West End
- Westminster Constituency
- Dundee Central
Further Information
Notice Documents
-
https://www.publiccontractsscotland.gov.uk/search/show/search_view.aspx?ID=JUN387322
Provision of project-specific sequencing services - Profiling of 360 FFPE samples using Illumina TruSeq RNA Exome with claraT reporting & DDIR evaluation
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