Tender

GB-London: RBGKEW1276 - Whole Genome Sequencing for cacao DNA from herbarium specimens

BIP SOLUTIONS LIMITED

This public procurement record has 1 release in its history.

Tender

17 Jan 2024 at 15:10

Tender Notice
Summary of the contracting process

The Royal Botanic Gardens, Kew (RBG Kew) is seeking a supplier for a whole genome sequencing service for cacao DNA sourced from historical herbarium collections. The procurement process involves conducting pre- and post-quality control tests, library preparation, and whole genomic sequencing. The tender, with an estimated value of £50,000, falls under the 'Research laboratory services' category and is located in London. The deadline for tender submissions is set for February 2, 2024, with the contract period scheduled from March 4, 2024, to September 3, 2025.

This tender opportunity, initiated by BIP SOLUTIONS LIMITED, is open to small and medium enterprises (SMEs). Businesses specialised in high-throughput sequencing from aged herbarium samples are well-suited to compete. The procurement method is an 'Open procedure (below threshold)', presenting a chance for interested parties to contribute towards RBG Kew's project on studying the geographical history and population genomics of Theobroma cacao. The contract aims to support ongoing research activities and data collection efforts within the specified genomic sequencing project.

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Notice Information

Notice Title

GB-London: RBGKEW1276 - Whole Genome Sequencing for cacao DNA from herbarium specimens

Notice Description

The Royal Botanic Gardens, Kew (RBG Kew) intends to appoint a supplier for a high-throughput sequencing service from ancient-DNA extractions sourced from historical herbarium collections of cacao specimens (Theobroma cacao, Malvaceae) and wild relative species (Theobroma/Herrania spp.). Utilizing a CTAB-extraction method, the extracted samples will be sent in batches. The supplier must conduct pre-quality control (QC) tests (including RNase treatment and DNA purification, if necessary) on these total-genome DNA extractions, ensuring acceptable yields and concentrations. Tasks also include library preparation using the Nextera XT Library Kit and performing paired-end whole genomic sequencing (WGS) using the Illumina NovaSeq 6000 (or an equally powerful sequencing platform) to seek obtaining ideally ~12 Gb per sample, depending on the conditions of the sample. This process aims to cover 120-140 samples, targeting a coverage of 15-30x each, given the known genome size of Theobroma species at ~450-490 Mbp. The supplier should be acquainted with high-throughput sequencing from aged herbarium samples, due to the historical nature of these collections (preserved over 50-100 years ago). They are expected to have previous experience in the production of satisfactory data under these conditions and will need to state this in the application. Each sample sent will contain 25-50 uL of DNA, predominantly at concentrations of 10 ng/uL (some with less, but never less than 0.5 ng/uL of total DNA). It is expected that many samples will have heavily fragmented DNA, and the supplier should be able to present alternatives to deal with these. Following sequencing, the supplier should conduct post-QC to verify data quality before delivery. Data transfer methods such as USB, HDD, or preferably Cloud transfer are viable options. The genomic data obtained will support an ongoing project at RBG Kew. This project aims to comprehensively study the geographical history, and other population genomic studies of Theobroma cacao at a global scale, utilising molecular data obtained from historical herbarium collections combined with data obtained from other sources. Additional information: The contracting authority considers that this contract may be suitable for economic operators that are small or medium enterprises (SMEs). However, any selection of tenderers will be based solely on the criteria set out for the procurement.

Notice Details

Publication & Lifecycle

Open Contracting ID
ocds-b5fd17-da21aad7-c536-4017-a0c7-b17be7c67ddb
Publication Source
Contracts Finder
Latest Notice
https://www.contractsfinder.service.gov.uk/Notice/9b27dfa9-07d7-498c-abbe-42f233eb694f
Current Stage
Tender
All Stages
Tender

Procurement Classification

Notice Type
Tender Notice
Procurement Type
Standard
Procurement Category
Services
Procurement Method
Open
Procurement Method Details
Open procedure (below threshold)
Tender Suitability
SME
Awardee Scale
Not specified

Common Procurement Vocabulary (CPV)

CPV Divisions

73 - Research and development services and related consultancy services

CPV Codes

73111000 - Research laboratory services

Notice Value(s)

Tender Value
£50,000 Under £100K
Lots Value
Not specified
Awards Value
Not specified
Contracts Value
Not specified

Notice Dates

Publication Date
17 Jan 20242 years ago
Submission Deadline
2 Feb 2024Expired
Future Notice Date
Not specified
Award Date
Not specified
Contract Period
4 Mar 2024 - 3 Sep 2025 1-2 years
Recurrence
Not specified

Notice Status

Tender Status
Active
Lots Status
Not Specified
Awards Status
Not Specified
Contracts Status
Not Specified

Buyer & Supplier

Contracting Authority (Buyer)

Main Buyer
BIP SOLUTIONS LIMITED
Contact Name
Available with D3 Tenders Premium →
Contact Email
Available with D3 Tenders Premium →
Contact Phone
Available with D3 Tenders Premium →

Buyer Location

Locality
LONDON
Postcode
TW9 3AB
Post Town
Twickenham
Country
England
Major Region (ITL 1)
TLI London
Basic Region (ITL 2)
TLI7 Outer London - West and North West
Small Region (ITL 3)
TLI75 Hounslow and Richmond upon Thames
Delivery Location
TLI London
Local Authority
Richmond upon Thames
Electoral Ward
Kew
Westminster Constituency
Richmond Park

Further Information

Open Contracting Data Standard (OCDS)

View full OCDS Record for this contracting process

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The Open Contracting Data Standard (OCDS) is a framework designed to increase transparency and access to public procurement data in the public sector. It is widely used by governments and organisations worldwide to report on procurement processes and contracts. 

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