Notice Information
Notice Title
Investigation of bacterial involvement in canine CRGV cases
Notice Description
Canine cutaneous and renal glomerular vasculopathy (CRGV and sometimes known as 'Alabama rot') in the UK first appeared in 2012, with 4 cases presenting to a Anderson Moores from practices around the New Forest, Hampshire with acute kidney injury (AKI) and skin lesions. The numbers of cases and geographical distribution of the disease have in the main increased year on year, with 190 cases now reported. The disease is normally characterised by the initial appearance of skin lesions on the limbs +/- face and body. Some dogs then go on to develop acute deterioration of kidney function and death. On post mortem blood vessels are seen to be blocked by thrombi (clots). The cause of the disease is unknown, despite investigation. Tests undertaken include investigation for E.coli (given some similarities to human haemolytic uremic syndrome), Circovirus, pan viral metagenomics and bacterial 16S probes, heavy metals and ethylene glycol poisoning. Leptospira has been investigated as a cause, and although presence of this organism was high in cases, results couldn't indicate a causative link. Despite the extensive investigations already undertaken, a few bacterial causes remain possible based upon experimental results or pathological findings. Toxigenic bacteria have not been found in the kidneys, but this does not rule out their presence in the skin lesions, with local production of toxins into the circulation causing subsequent kidney injury. Shiga toxigenic E. coli were hypothesised to cause similar disease in the USA with kidney injury. Aeromonas hydrophilia causes similar skin lesions in fish and amphibians with subsequent kidney failure, as well as disease in humans, and are also toxigenic, with toxin production in limbs causing organ injury. Leptospira were unusually prevalent in cases and can cause kidney injury. Without an analysis of cases vs healthy animals it is impossible to confirm the likely association of these bacteria (Aeromonas, E.coli and Leptospira Additional information: Please note that Defra procurement uses an E-tendering system for Procurement activities. This is currently provided by Bravo Solutions. To access appropriate tendering and contractual documents, please access the E-Tendering portal at https://defra.bravosolution.co.uk", ensuring that your registration includes "Defra". If you have any problems with this system, please contact Bravo on their telephone helpline number 0800 368 4850 or by emailing them at help@bravosolution.co.uk. "
Notice Details
Publication & Lifecycle
- Open Contracting ID
- ocds-b5fd17-ec9dc124-696d-441a-9f42-c16ffe0310fe
- Publication Source
- Contracts Finder
- Latest Notice
- https://www.contractsfinder.service.gov.uk/Notice/6e222e4d-4d48-4081-b335-053e0aba96d7
- Current Stage
- Award
- All Stages
- Award
Procurement Classification
- Notice Type
- Award Notice
- Procurement Type
- Standard
- Procurement Category
- Services
- Procurement Method
- Direct
- Procurement Method Details
- Single tender action (below threshold)
- Tender Suitability
- SME
- Awardee Scale
- Large
Common Procurement Vocabulary (CPV)
- CPV Divisions
73 - Research and development services and related consultancy services
-
- CPV Codes
73000000 - Research and development services and related consultancy services
Notice Value(s)
- Tender Value
- Not specified
- Lots Value
- Not specified
- Awards Value
- £25,000 Under £100K
- Contracts Value
- Not specified
Notice Dates
- Publication Date
- 20 Apr 20205 years ago
- Submission Deadline
- 1 Oct 2019Expired
- Future Notice Date
- Not specified
- Award Date
- 10 Feb 20206 years ago
- Contract Period
- 1 Nov 2019 - 31 Mar 2020 1-6 months
- Recurrence
- Not specified
Notice Status
- Tender Status
- Complete
- Lots Status
- Not Specified
- Awards Status
- Active
- Contracts Status
- Not Specified
Buyer & Supplier
Contracting Authority (Buyer)
- Main Buyer
- DEFRA NETWORK ETENDERING PORTAL
- Contact Name
- Available with D3 Tenders Premium →
- Contact Email
- Available with D3 Tenders Premium →
- Contact Phone
- Available with D3 Tenders Premium →
Buyer Location
- Locality
- LONDON
- Postcode
- SW1P 3JR
- Post Town
- South West London
- Country
- England
-
- Major Region (ITL 1)
- TLI London
- Basic Region (ITL 2)
- TLI3 Inner London - West
- Small Region (ITL 3)
- TLI35 Westminster and City of London
- Delivery Location
- Not specified
-
- Local Authority
- Westminster
- Electoral Ward
- St James's
- Westminster Constituency
- Cities of London and Westminster
Further Information
Notice Documents
-
https://www.contractsfinder.service.gov.uk/Notice/6e222e4d-4d48-4081-b335-053e0aba96d7
20th April 2020 - Awarded contract notice on Contracts Finder -
Open Contracting Data Standard (OCDS)
View full OCDS Record for this contracting process
The Open Contracting Data Standard (OCDS) is a framework designed to increase transparency and access to public procurement data in the public sector. It is widely used by governments and organisations worldwide to report on procurement processes and contracts.
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