Additional Analytical Methods for NDNS Biomonitoring

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            "id": "GB-PPON-PJRM-6866-LYYX",
            "name": "Food Standards Agency",
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                "name": "FSA Commercial",
                "email": "fsa.commercial@food.gov.uk"
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                "description": "The Food Standards Agency (FSA) is undertaking pre-market engagement to inform a potential future procurement for the development and validation of analytical methods to support biomonitoring of food additives and chemical contaminants. This engagement seeks to: Test the feasibility of identifying and quantifying suitable urinary biomarkers for priority additive and contaminant groups Understand market capability and capacity to deliver analytical method development and validation within the proposed timeframes and budget Gather insight into available methodologies (e.g. LC-MS, GC-MS, ICP-MS) and approaches to biomarker identification, including limitations and innovation opportunities Inform the future procurement strategy, including lot structure, specification design, achievable scope, and value for money considerations Suppliers are invited to provide feedback on the proposed scope, including: Feasibility of delivering the requirements within ~10 months per lot The number and type of substances that could realistically be covered within the indicative budget Approaches to biomarker selection, ADME evaluation, and method validation Any risks, constraints, or dependencies that should be considered The information gathered will be used solely to shape the FSA's understanding of the market and to refine a potential future competitive procurement. Participation is voluntary, and non-participation will not disadvantage suppliers in any subsequent procurement process. All documents and communication for FSA funded projects must be submitted through the health-family single e-Commercial System (Atamis), using the following link: https://health-family.force.com/s/Welcome",
                "dueDate": "2026-06-15T23:59:59+01:00",
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        "title": "Additional Analytical Methods for NDNS Biomonitoring",
        "description": "Tenders are invited to undertake a research project to identify suitable biomarkers of priority (groups of) additives (Lot 1) and contaminants (Lot 2), Metals (Lot 3) and develop and validate analytical chemistry methods for their quantitative measurement in human urine. In addition, an approach for estimating systemic exposure and theoretical dietary intake of each chemical of interest, from measured urinary excretion of the biomarker(s), should be derived. The FSA is requesting that methods and approaches are determined, and proven for feasibility, for substances from the following food additive and other chemical contaminant groups, below or up to the estimated budget of PS100,000 (exc. VAT) Lot 1 and PS50,000 (exc VAT) each for lot 2 and 3. The substance groups have been prioritised in accordance with the FSA's food safety remit and specific priorities. All documents and communication for FSA funded projects must be submitted through the health-family single e-Commercial System (Atamis), using the following link: https://health-family.force.com/s/Welcome",
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                "title": "Lot 1: Food Additives",
                "description": "Food Additives (Lot 1) Over 300 food additives are approved for use in food in Great Britain (GB) (not including different forms of the same substance), and these are described in the FSA's list of Approved additives and E numbers | Food Standards Agency. Food additives are ingredients that are added to foods to carry out a particular technological function, but they may only be used in food for which they have been authorised and only up to their maximum permitted level. However, the actual use levels of food additives in foods may be below the maximum permitted levels and, therefore, accurate consumer exposures to additives in foods are not easy to estimate. Additionally, consumers may be exposed to additives through different sources, and other factors, such as dietary preferences and brand loyalty, can often make the estimation of actual exposure challenging.",
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                "title": "Lot 2 : Chemical Contaminants",
                "description": "Chemical Contaminants (Lot 2) Chemical contaminants in food are unintentional and undesirable substances that may pose health risks at certain levels. Some examples of chemical contaminants include mycotoxins, heavy metals (such as lead and mercury), and organic pollutants (like dioxins). Chemical contaminants can enter the food chain from multiple sources, during primary or secondary production. Because of their potential impact on health, regulatory controls exist to limit consumer exposure, and it is essential to manage and reduce their presence in food.",
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                "description": "Analysis of biomarkers able to inform on exposure to the heavy metals, arsenic, cadmium, and lead. If it is technically feasible and cost effective, analysis of other metals that may be relevant to food safety may be proposed in the response to tender, in 400 NDNS Bioresource urine samples. Measurement of urinary creatinine concentration to account for urine dilution and to enable estimation of exposure. Demonstration of an approach to estimating dietary intake of relevant metals from measured concentration of biomarker",
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            "financialTerms": "Payment of valid and undisputed invoices will be made within 30 days of receipt of the invoice or, if later, the date by which the payment falls due in accordance with the invoice, which must be submitted promptly by the Supplier. All invoices must be sent, quoting a valid Purchase Order Number (PO Number) and any other relevant details including the minimum required information set out in Section 68(9) of the Procurement Act 2023, to: fsa.payments. Within 10 Working Days of receipt of your countersigned copy of this Order Form, we will send you a unique PO Number. You must be in receipt of a valid PO Number before submitting an invoice. To avoid delay in payment it is important that the invoice is compliant and that it includes a valid PO Number, item number (if applicable) and the details (name, email, and telephone number) of your Buyer contact (i.e., Buyer Authorised Representative). Non-compliant invoices may be sent back to you, which may lead to a delay in payment."
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