Tender

Supply of a Biophysical Equipment System

UNIVERSITY OF DUNDEE

This public procurement record has 1 release in its history.

Tender

29 Jun 2022 at 00:00

Summary of the contracting process

The University of Dundee is currently conducting a procurement process for the supply of a Biophysical Equipment System, aimed at enhancing biophysical characterisation capabilities essential for research into Proteolysis Targeting Chimeras (PROTACs) and molecular glues. This tender falls under the goods category within the education industry and is being hosted in Markinch, UK. The deadline for submissions is set for 29 July 2022 at 12:00 GMT, with the tender period closing at the same time. The procurement method is an open procedure, allowing a diverse range of businesses to participate.

This tender presents significant opportunities for businesses specialising in high-tech biophysical equipment and molecular characterisation tools, particularly those with capabilities in developing systems that can handle complex sample requirements. Companies focusing on advanced scientific instrumentation or related technologies could find this tender well-suited to their offerings. Engaging in this process could also foster partnerships with academic institutions and enhance visibility within the research community, which is increasingly focused on innovative biophysical methods.

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Notice Title

Supply of a Biophysical Equipment System

Notice Description

Biophysical characterization of binary and ternary complex formations in proximity-inducing compounds is a key step in the iterative improvement of potency of Proteolysis Targeting Chimeras (PROTACs) and molecular glues. In order for us to have the ability to scrutinise the affinity and kinetics of binary and ternary complexes with challenging sample requirements (e.g. low affinity (1-10 uM) complexes, low protein availability, homoPROTACs etc) highly specialised systems are required. The technique will provide a readout of compound/PROTAC affinity while providing insight into additional biophysical parameters, all of which can be critical for compound optimization/prioritization. This tender aims to substantially increase the ability of biophysicists and chemists to assess PROTAC/molecular glue biophysics and will be complimentary to techniques currently available to the new Center for Targeted Protein Degradation (CeTPD) (including SPR, ITC, TR-FRET) while being able to probe interactions that other techniques cannot currently scrutinise. The new machine will be housed in the CeTPD.

Lot Information

Lot 1

Biophysical characterization of binary and ternary complex formations in proximity-inducing compounds is a key step in the iterative improvement of potency of Proteolysis Targeting Chimeras (PROTACs) and molecular glues. In order for us to have the ability to scrutinise the affinity and kinetics of binary and ternary complexes with challenging sample requirements (e.g. low affinity (1-10 uM) complexes, low protein availability, homoPROTACs etc) highly specialised systems are required. The technique will provide a readout of compound/PROTAC affinity while providing insight into additional biophysical parameters, all of which can be critical for compound optimization/prioritization. This tender aims to substantially increase the ability of biophysicists and chemists to assess PROTAC/molecular glue biophysics and will be complimentary to techniques currently available to the new Center for Targeted Protein Degradation (CeTPD) (including SPR, ITC, TR-FRET) while being able to probe interactions that other techniques cannot currently scrutinise. The new machine will be housed in the CeTPD.

Renewal: Extended warranty/service if taken out later and not at time of equipment purchase.

Publication & Lifecycle

Open Contracting ID
ocds-r6ebe6-0000698752
Publication Source
Public Contracts Scotland
Latest Notice
https://www.publiccontractsscotland.gov.uk/search/show/search_view.aspx?ID=JUN452628
Current Stage
Tender
All Stages
Tender

Procurement Classification

Notice Type
OJEU - F2 - Contract Notice
Procurement Type
Standard
Procurement Category
Goods
Procurement Method
Open
Procurement Method Details
Open procedure
Tender Suitability
Not specified
Awardee Scale
Not specified

Common Procurement Vocabulary (CPV)

CPV Divisions

38 - Laboratory, optical and precision equipments (excl. glasses)


CPV Codes

38000000 - Laboratory, optical and precision equipments (excl. glasses)

Notice Value(s)

Tender Value
Not specified
Lots Value
Not specified
Awards Value
Not specified
Contracts Value
Not specified

Notice Dates

Publication Date
29 Jun 20223 years ago
Submission Deadline
29 Jul 2022Expired
Future Notice Date
Not specified
Award Date
Not specified
Contract Period
Not specified - Not specified
Recurrence
Not specified

Notice Status

Tender Status
Active
Lots Status
Active
Awards Status
Not Specified
Contracts Status
Not Specified

Contracting Authority (Buyer)

Main Buyer
UNIVERSITY OF DUNDEE
Contact Name
Tracy Templeman
Contact Email
t.templeman@dundee.ac.uk
Contact Phone
+44 1382386810

Buyer Location

Locality
MARKINCH
Postcode
DD1 4HN
Post Town
Dundee
Country
Scotland

Major Region (ITL 1)
TLM Scotland
Basic Region (ITL 2)
TLM0 Eastern Scotland
Small Region (ITL 3)
TLM03 Angus and Dundee City
Delivery Location
TLM71 Angus and Dundee City

Local Authority
Dundee City
Electoral Ward
West End
Westminster Constituency
Dundee Central

Further Information

Notice Documents

Open Contracting Data Standard (OCDS)

View full OCDS Record for this contracting process

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The Open Contracting Data Standard (OCDS) is a framework designed to increase transparency and access to public procurement data in the public sector. It is widely used by governments and organisations worldwide to report on procurement processes and contracts.

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