Planning

Upgrade of the freeze-drying microscope for determination of the collapse temperature (Tc) and the eutectic point (Teu) of formulations

MEDICINES AND HEALTHCARE PRODUCTS REGULATORY AGENCY

This public procurement record has 2 releases in its history.

Planning

24 Sep 2019 at 12:27

Planning

24 Jan 2019 at 16:59

Summary of the contracting process

The Medicines and Healthcare Products Regulatory Agency is currently in the planning stage of a procurement process titled "Upgrade of the freeze-drying microscope for determination of the collapse temperature (Tc) and the eutectic point (Teu) of formulations". This project, categorised under microbiological cultures, involves upgrading an existing freeze-drying microscope that has been in use for over a decade. Potential suppliers should take note of the deadline for expressing interest, which is set for 19 February 2019, and the delivery is expected in the East of England.

This tender presents a significant opportunity for businesses in the fields of scientific instrumentation and laboratory equipment manufacturing. Companies that specialise in advanced microscopy technology, particularly those with expertise in freeze-drying systems, would find this contract particularly relevant. Small and medium enterprises (SMEs) are encouraged to participate, as there is a focus on using SME suppliers for this procurement, thus opening pathways for growth and collaboration within the sector.

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Notice Title

Upgrade of the freeze-drying microscope for determination of the collapse temperature (Tc) and the eutectic point (Teu) of formulations

Notice Description

Agency need to upgrade existing Freeze-Drying Microscope, as the current unit is more than 10 years old. A replacement system/unit must be able to perform to the same or higher capability as the current unit. It should be able to reproducibly determine the collapse and eutectic temperatures for a range of formulations and biological materials. Thus, allowing for the optimisation of lyophilisation cycles. Description: A suitable freeze-drying Microscope unit should consist of: 1. A temperature controller, ideally with a temperature and pressure readout and a programmable profile function for full control of the system during analysis. 2. A digital camera with a specification of at least 2.3 million pixels and a 12-bit digital colour output. 3. A Liquid nitrogen pump and Dewar containing a twin pump mechanism for faster cooling. 4. A vacuum gauge with a pressure range from atmospheric to 10-4 mBar and a motorised valve. 5. An imaging Station with articulated head for easy sample loading and cleaning, with dimmable LED source in combination with an efficient, custom-designed electronics module and polarised light filter. The lifetime of the LED should adequate such as but not limited to 60.000 hours and good to be maintenance free. Electrical power should be a maximum of 10.0W. The LED colour temperature ideally about 4500K. 6. A cryostage, such as but not limited to, FDCS 196 or equivalent. 7. A Workstation featuring minimum specification; Intel core i7 3.2GHz processor, 8GB RAM, 500GB hard drive, motherboard, Windows 10 (64 Bit), NET framework 4.0, USB 3.0 connection, HD Monitor, keyboard and mouse is preferable. 8. The temperature control, real-time digital video and measurement software should ideally have a live temperature and pressure information, allowing full monitoring and adjustment of experimental conditions, up to 80Gb file sizes with all captured images and experimental conditions and image compressors to create JPEG image files or AVI videos of the analysis. 9. Set-up, test and full system validation against a range of standard solutions with documented critical temperatures prior to dispatch. 10. Ongoing support for interpretation of results as required and an image analysis software package that helps to minimise subjectivity in determining Tc and Teu is desirable. Manufacturers would be required to demonstrate that their instrument can measure a range of standard solutions and their documented critical temperatures should be provided. Equipment size should be designed for benchtop and should not exceed: Width = 170cm (includes all the components), Depth = 60cm, Height = 100cm. A demonstration of each instrument capability at NIBSC (MHRA) is essential as well as onsite installation and training if successful. Potential suppliers if they feel they can meet the requirement should email Nawaz.habib@nibsc.org to register an interest by close of play 19 February 2019.

Publication & Lifecycle

Open Contracting ID
ocds-b5fd17-24bb25f4-9628-4434-8a2c-008ee619fe55
Publication Source
Contracts Finder
Latest Notice
https://www.contractsfinder.service.gov.uk/Notice/7260715c-04f9-4277-b1e3-80e06a87e288
Current Stage
Planning
All Stages
Planning

Procurement Classification

Notice Type
Market Engagement Notice
Procurement Type
Standard
Procurement Category
Not specified
Procurement Method
Not Specified
Procurement Method Details
Not specified
Tender Suitability
SME
Awardee Scale
Not specified

Common Procurement Vocabulary (CPV)

CPV Divisions

33 - Medical equipments, pharmaceuticals and personal care products

38 - Laboratory, optical and precision equipments (excl. glasses)

39 - Furniture (incl. office furniture), furnishings, domestic appliances (excl. lighting) and cleaning products

44 - Construction structures and materials; auxiliary products to construction (except electric apparatus)


CPV Codes

33698100 - Microbiological cultures

38510000 - Microscopes

38634000 - Optical microscopes

39711124 - Industrial freezers

44441000 - Microbeads

Notice Value(s)

Tender Value
Not specified
Lots Value
Not specified
Awards Value
Not specified
Contracts Value
Not specified

Notice Dates

Publication Date
24 Sep 20196 years ago
Submission Deadline
Not specified
Future Notice Date
19 Feb 2019Expired
Award Date
Not specified
Contract Period
Not specified - Not specified
Recurrence
Not specified

Notice Status

Tender Status
Planning
Lots Status
Not Specified
Awards Status
Not Specified
Contracts Status
Not Specified

Contracting Authority (Buyer)

Main Buyer
MEDICINES AND HEALTHCARE PRODUCTS REGULATORY AGENCY
Contact Name
Available with D3 Tenders Premium →
Contact Email
Available with D3 Tenders Premium →
Contact Phone
Available with D3 Tenders Premium →

Buyer Location

Locality
POTTERS BAR
Postcode
EN6 3QG
Post Town
Enfield
Country
England

Major Region (ITL 1)
TLH East (England)
Basic Region (ITL 2)
TLH2 Bedfordshire and Hertfordshire
Small Region (ITL 3)
TLH27 South West Hertfordshire
Delivery Location
Not specified

Local Authority
Hertsmere
Electoral Ward
Shenley
Westminster Constituency
Hertsmere

Open Contracting Data Standard (OCDS)

View full OCDS Record for this contracting process

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