Notice Information
Notice Title
Tender for the Supply and Installation of FRET/Ca2+ Imaging and 4-Camera TIRF Microscopes
Notice Description
The FRET/Ca2+ imaging and 4-camera TIRF microscopes are to be purchased by the Institute of Metabolism and Systems Research (IMSR), UoB. Match funding will be provided through COMPARE (http://www.birmingham-nottingham.ac.uk/compare/index.aspx). The systems will be housed in the recently refurbished rooms of the Centre of Membrane Proteins and Receptors (COMPARE). Access will be granted to members of COMPARE, as well as the intravital microscopy (IVM) user group. The specification below specifications outline the requirements for: a. A FRET/Ca2+ imaging microscope, which must be capable of performing fast high-sensitivity ratiometric imaging and photometric measurements in cells expressing FRET reporters or loaded with Ca2+ indictors (e.g. Fura-2). The system should be equipped with a monochromator for maximal flexibility and speed in the selection of the excitation wavelength, a dual-camera beam splitter, a very high sensitivity camera (EMCCD or equivalent). In addition, it should be equipped with a photomultiplier-based ratiometric acquisition system allowing ultrafast kinetics measurements (up to 100 microsecond temporal resolution). The system should also be equipped with a caged incubator for temperature control and a laminar-flow superfusion system (or more if needed) with compatible imaging chamber allowing both ultrarapid exchange of solutions (< 2 ms) and long superfusion times (up to 1 hour). The perfusion systems/imaging chambers/stage insets should be ideally interchangeable and could be shared between the two microscopes, allowing maximal flexibility. The microscope should be controlled by a user-friendly software, allowing the real-time monitoring of ratiometric FRET and Ca2+ traces and the control/recording of the triggers to/from the perfusion system(s). b. A 4-channel 2D/3D TIRF microscope for the analysis of both fast and slow dynamic biological processes (from few milliseconds to 1 hour) in living cells by single-molecule microscopy/single-particle tracking, superresolution microscopy methods such as 2D/3D PALM/dSTORM and single-molecule FRET. The system should also allow the fast and simultaneous acquisition of FRET between CFP and YFP by ratiometric imaging and single-molecule acquisition in the red or far-red channel. The system should also ideally allow to perform FRAP and/or uncaging experiments. The system should be equipped with suitable solid-state lasers of adequate power, a TIRF illuminator providing homogenous illumination, a quadruple camera beam-splitter and four fast EMCCD cameras. The microscope should be controlled by a user-friendly software, allowing fast synchronised real-time acquisition from the four cameras (>= 56 frames/s in normal full-frame 512x512 mode and >= 560 frames/s from a 128x128 sub-array in crop mode). The system should also be equipped with a caged incubator for temperature control and a laminar-flow superfusion system (or more if needed) with compatible imaging chambe... Additional information: Please log in or register to find documents at www.in-tendhost.com/universityofbirmingham Is a Recurrent Procurement Type? : No
Notice Details
Publication & Lifecycle
- Open Contracting ID
- ocds-b5fd17-eb284efb-0d58-43ab-bfa4-9010c7c0f1b8
- Publication Source
- Contracts Finder
- Latest Notice
- https://www.contractsfinder.service.gov.uk/Notice/d30ef6a3-af4c-439e-9921-53c8bfaef304
- Current Stage
- Tender
- All Stages
- Tender
Procurement Classification
- Notice Type
- Tender Notice
- Procurement Type
- Standard
- Procurement Category
- Goods
- Procurement Method
- Open
- Procurement Method Details
- Open procedure (above threshold)
- Tender Suitability
- SME
- Awardee Scale
- Not specified
Common Procurement Vocabulary (CPV)
- CPV Divisions
38 - Laboratory, optical and precision equipments (excl. glasses)
-
- CPV Codes
38510000 - Microscopes
Notice Value(s)
- Tender Value
- Not specified
- Lots Value
- Not specified
- Awards Value
- Not specified
- Contracts Value
- Not specified
Notice Dates
- Publication Date
- 9 Oct 20178 years ago
- Submission Deadline
- 8 Nov 2017Expired
- Future Notice Date
- Not specified
- Award Date
- Not specified
- Contract Period
- 1 Dec 2017 - 30 Mar 2018 1-6 months
- Recurrence
- Not specified
Notice Status
- Tender Status
- Active
- Lots Status
- Not Specified
- Awards Status
- Not Specified
- Contracts Status
- Not Specified
Buyer & Supplier
Contracting Authority (Buyer)
- Main Buyer
- UNIVERSITY OF BIRMINGHAM
- Contact Name
- Available with D3 Tenders Premium →
- Contact Email
- Available with D3 Tenders Premium →
- Contact Phone
- Available with D3 Tenders Premium →
Buyer Location
- Locality
- EDGBASTON
- Postcode
- B15 2TT
- Post Town
- Birmingham
- Country
- England
-
- Major Region (ITL 1)
- TLG West Midlands (England)
- Basic Region (ITL 2)
- TLG3 West Midlands
- Small Region (ITL 3)
- TLG31 Birmingham
- Delivery Location
- Not specified
-
- Local Authority
- Birmingham
- Electoral Ward
- Edgbaston
- Westminster Constituency
- Birmingham Edgbaston
Further Information
Notice Documents
-
https://www.contractsfinder.service.gov.uk/Notice/d30ef6a3-af4c-439e-9921-53c8bfaef304
9th October 2017 - Opportunity notice on Contracts Finder -
https://in-tendhost.co.uk/universityofbirmingham/aspx/
Additional information on how to apply for this contract
Open Contracting Data Standard (OCDS)
View full OCDS Record for this contracting process
The Open Contracting Data Standard (OCDS) is a framework designed to increase transparency and access to public procurement data in the public sector. It is widely used by governments and organisations worldwide to report on procurement processes and contracts.
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