Award

OrbiSIMS - simultaneous high-mass resolving power and high-spatial resolution mass spectrometry imaging for biological and advanced materials characterisation

NATIONAL PHYSICAL LABORATORY

This public procurement record has 1 release in its history.

Award

23 Jan 2023 at 16:45

Summary of the contracting process

The National Physical Laboratory (NPL) has recently completed the OrbiSIMS procurement process for simultaneous high-mass resolving power and high-spatial resolution mass spectrometry imaging equipment designed for biological and advanced materials characterisation. The procurement falls under the category of Laboratory, optical and precision equipments, and the procurement method used was an award procedure without prior publication of a call for competition. NPL located in Teddington, UK, was the buying organization, with the tender being in the goods category. The procurement stage has reached the award phase, with the contractual agreement signed on 23rd January 2023.

This tender for the OrbiSIMS equipment, awarded to IONTOF GmbH, presents a growth opportunity for businesses involved in laboratory equipment manufacturing, particularly those specialising in high-tech mass spectrometry devices. Companies with expertise in developing cutting-edge analytical instruments for biological and materials research would be well-suited to compete in such tenders. The innovative features and high specifications required for the OrbiSIMS instrument indicate a need for businesses with advanced technology capabilities and a track record of delivering precision scientific equipment.

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Notice Title

OrbiSIMS - simultaneous high-mass resolving power and high-spatial resolution mass spectrometry imaging for biological and advanced materials characterisation

Notice Description

NPL pioneered the next generation OrbiSIMS technology introduced in detail in Nature Methods (2017, PMID: 29131162). The instrument is equipped with a time-of-flight mass spectrometer (ToF) for high-speed imaging of large areas or in 3D. It is also equipped with a high-field Orbitrap mass spectrometer with a mass resolving power of >240,000 at m/z 200 and a mass accuracy of approximately 1 ppm. Both ToF and Orbitrap analysers can be used simultaneously or separately. The OrbiSIMS shall be able to carry out cryogenic analysis under ultra-high vacuum with sample holder temperatures below -150 oC.

Lot Information

Lot 1

The OrbiSIMS instrument shall be equipped with a time-of-flight mass spectrometer (ToF) for high-speed imaging of large areas or in 3D. It shall also be equipped with a high-field Orbitrap mass spectrometer with a mass resolving power of >240,000 at m/z 200 and a mass accuracy of ~ 1 ppm. The instrument shall be equipped with 3 primary ion beams which are optimal for different materials systems. (1) A 20 kV gas cluster ion source with a spatial resolution < 2 um used for biological imaging and depth-profiling of organic materials, (2) a low energy (250 eV to 2000 eV) dual source (Cs and O2) sputter beam with high-current (>50 nA at 500 eV with a spatial resolution < 40 um) for depth profiling of semiconductor samples and (3) a 30 kV high-resolution Bi nanoprobe with a spatial resolution < 50 nm. The instrument shall be able to operate with either the ToF analyser or the Orbitrap analyser or a combination of the two as described in the Nat. Methods paper. (4) a Ga focused ion beam with accelerating voltages of up to 30 kV, minimum bema diameter of 60nm and beam current > 25 nA. The OrbiSIMS shall be equipped for cryogenic analysis (sample holder temperature < -150 oC) and be compatible with and including Leica sample holders and allow the docking of a Leica VCT-500 cryo transfer vessel. It shall have two high-resolution TV cameras for direct sample observation and rapid location of the area of interest, as well as a photo box for high-resolution sample navigation. In addition to mass analysers, the instrument shall have a pulsed high-quality Everhart-Thornley secondary electron detector, located at grazing incidence to the sample, for primary ion induced secondary electron imaging and a self-adjusting charge compensation system using a pulsed, low energy electron flood gun. Samples shall be mounted using a rapid sample introduction system, with one sample holder for rear mounting of up to 18 samples with maximum dimensions of 10 mm x 10 mm x 8 mm, including mounting accessories, one sample holder for top mounting of multiple samples on an area of 100 mm x 80 mm with a maximum thickness of up to 20 mm, and one sample holder for mounting samples for cryogenic analysis.

Procurement Information

The OrbiSIMS concept was created at NPL and the first prototype instrument was built in a collaborative project with IONTOF and ThermoFisher Scientific. The instrument was subsequently commercialised by IONTOF and sold as the Hybrid SIMS. IONTOF are the only manufacturer of this type of instrument. A number of features of the OrbiSIMS instrument are protected by international patents. Unique features of the OrbiSIMS instrument include: 1. Imaging of biomolecules from tissue using a gas cluster ion beam with a spatial resolution of < 2 um simultaneously with a mass resolving power of > 240,000 at m/z 200. 2. Depth resolution of < 10 nm of organic molecules in an organic multilayer reference sample simultaneously with a mass resolving power of > 240,000 at m/z 200. 3. Depth resolution of < 2 nm of ions in an inorganic semiconductor delta-layer reference sample simultaneously with a mass resolving power of > 240,000 at m/z 200. 4. Cryogenic imaging (see requirement 1) with a sample holder temperature of < -150 oC. Samples shall be mounted on Leica sample mounts. The instrument shall accept docking of a Leica VCT-500 cryo transfer vessel and have provision to receive samples into the instrument.

Publication & Lifecycle

Open Contracting ID
ocds-h6vhtk-0399e3
Publication Source
Find A Tender Service
Latest Notice
https://www.find-tender.service.gov.uk/Notice/002057-2023
Current Stage
Award
All Stages
Award

Procurement Classification

Notice Type
Award Notice
Procurement Type
Standard
Procurement Category
Goods
Procurement Method
Limited
Procurement Method Details
Award procedure without prior publication of a call for competition
Tender Suitability
Not specified
Awardee Scale
Large

Common Procurement Vocabulary (CPV)

CPV Divisions

38 - Laboratory, optical and precision equipments (excl. glasses)


CPV Codes

38000000 - Laboratory, optical and precision equipments (excl. glasses)

Notice Value(s)

Tender Value
Not specified
Lots Value
Not specified
Awards Value
Not specified
Contracts Value
Not specified

Notice Dates

Publication Date
23 Jan 20233 years ago
Submission Deadline
Not specified
Future Notice Date
Not specified
Award Date
23 Jan 20233 years ago
Contract Period
Not specified - Not specified
Recurrence
Not specified

Notice Status

Tender Status
Complete
Lots Status
Not Specified
Awards Status
Active
Contracts Status
Active

Contracting Authority (Buyer)

Main Buyer
NATIONAL PHYSICAL LABORATORY
Contact Name
Mandy Morgan
Contact Email
mandy.morgan@npl.co.uk
Contact Phone
+44 2089436731

Buyer Location

Locality
TEDDINGTON
Postcode
TW11 0LW
Post Town
Twickenham
Country
England

Major Region (ITL 1)
TLI London
Basic Region (ITL 2)
TLI7 Outer London - West and North West
Small Region (ITL 3)
TLI75 Hounslow and Richmond upon Thames
Delivery Location
Not specified

Local Authority
Richmond upon Thames
Electoral Ward
Teddington
Westminster Constituency
Twickenham

Supplier Information

Number of Suppliers
1
Supplier Name

IONTOF

Open Contracting Data Standard (OCDS)

View full OCDS Record for this contracting process

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The Open Contracting Data Standard (OCDS) is a framework designed to increase transparency and access to public procurement data in the public sector. It is widely used by governments and organisations worldwide to report on procurement processes and contracts.

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