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TIMSTOF Flex MALDI-2: A Quadrupole TOF instrument capable of rapid MALDI MS imaging with high spatial resolution, laser post-ionisation and ion mobility separation

NATIONAL PHYSICAL LABORATORY

This public procurement record has 1 release in its history.

Award

20 Feb 2023 at 16:26

Summary of the contracting process

The National Physical Laboratory in the UK has awarded a contract for the procurement of a TIMSTOF Flex MALDI-2 instrument for high throughput mass spectrometry imaging studies. The instrument, purchased from Bruker UK Ltd, features advanced MALDI-2 post-ionisation technology and high spatial resolution capabilities. The contract, valued at £1,600,000 GBP, was signed on 20th February 2023.

This tender presents an opportunity for businesses specialising in laboratory, optical, and precision equipment to provide innovative solutions for high spatial resolution mass spectrometry imaging. Companies with expertise in MALDI technology and ion mobility separation are well-suited to compete in this tender. The procurement method used was a limited award procedure without prior publication of a call for competition, tailored to the unique features of the required instrument.

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Notice Title

TIMSTOF Flex MALDI-2: A Quadrupole TOF instrument capable of rapid MALDI MS imaging with high spatial resolution, laser post-ionisation and ion mobility separation

Notice Description

Our large-scale mass spectrometry imaging (MSI) studies require high throughput, high spatial resolution MSI analysis of multiple tissue sections, on multiple slides. Currently, of commercially available MSI instruments, matrix assisted laser desorption ionisation (MALDI) provides the best combination of spatial resolution and throughput. Crucially, high sensitivity for both lipids and metabolites must also be achieved. MALDI-2 has recently been shown to provide unrivalled limit-of-detection for a range of lipid and metabolite classes at high spatial resolution. The Bruker timsTOF Flex MALDI-2 instrument is the only commercially available instrument to feature MALDI-2 post ionisation and 5um pixel size MSI

Lot Information

Lot 1

Matrix assisted laser desorption ionisation (MALDI) provides the highest commercially available spatial resolution for high throughput multi-slide analysis of biological samples by MSI. Recent advances in laser post-ionisation, termed MALDI-2, have demonstrated significant improvement in limit-of-detection for a range of analyte classes. The timsToF Flex MALDI-2 microGRID instrument should feature a dual electrospray and MALDI MSI ion source. It should feature MALDI-2 laser post-ionisation functionality and 5 um pixel size microGRID technology. It should provide 60,000 mass resolving power and scan rates of 20Hz. The instrument should also provide trapped ion mobility separation technology (TIMS) MSI functionality.

Procurement Information

The Bruker timsTOF Flex with MALDI-2 is the only commercially available instrument to provide MALDI-2 post ionisation withiwth high throughput imaging at 5 um pixel size. Unique features of this instrument include: 1. MALDI MSI with MALDI-2 post-ionisation MSI 2. MALDI MSI 5 um pixel size microGRID technology 3. Trapped ion mobility spectrometry with MALDI imaging and MALDI-2 post-ionisation

Publication & Lifecycle

Open Contracting ID
ocds-h6vhtk-03a6fb
Publication Source
Find A Tender Service
Latest Notice
https://www.find-tender.service.gov.uk/Notice/005077-2023
Current Stage
Award
All Stages
Award

Procurement Classification

Notice Type
Award Notice
Procurement Type
Standard
Procurement Category
Goods
Procurement Method
Limited
Procurement Method Details
Award procedure without prior publication of a call for competition
Tender Suitability
Not specified
Awardee Scale
Large

Common Procurement Vocabulary (CPV)

CPV Divisions

38 - Laboratory, optical and precision equipments (excl. glasses)


CPV Codes

38000000 - Laboratory, optical and precision equipments (excl. glasses)

Notice Value(s)

Tender Value
Not specified
Lots Value
Not specified
Awards Value
Not specified
Contracts Value
£1,600,000 £1M-£10M

Notice Dates

Publication Date
20 Feb 20233 years ago
Submission Deadline
Not specified
Future Notice Date
Not specified
Award Date
20 Feb 20233 years ago
Contract Period
Not specified - Not specified
Recurrence
Not specified

Notice Status

Tender Status
Complete
Lots Status
Not Specified
Awards Status
Active
Contracts Status
Active

Contracting Authority (Buyer)

Main Buyer
NATIONAL PHYSICAL LABORATORY
Contact Name
Not specified
Contact Email
mandy.morgan@npl.co.uk
Contact Phone
+44 2089776731

Buyer Location

Locality
TEDDINGTON
Postcode
TW11 0LW
Post Town
Twickenham
Country
England

Major Region (ITL 1)
TLI London
Basic Region (ITL 2)
TLI7 Outer London - West and North West
Small Region (ITL 3)
TLI75 Hounslow and Richmond upon Thames
Delivery Location
Not specified

Local Authority
Richmond upon Thames
Electoral Ward
Teddington
Westminster Constituency
Twickenham

Supplier Information

Number of Suppliers
1
Supplier Name

BRUKER

Open Contracting Data Standard (OCDS)

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The Open Contracting Data Standard (OCDS) is a framework designed to increase transparency and access to public procurement data in the public sector. It is widely used by governments and organisations worldwide to report on procurement processes and contracts.

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