Supply, Delivery and Commissioning of a Crystallisation Reactor

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        "title": "Supply, Delivery and Commissioning of a Crystallisation Reactor",
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        "procurementMethod": "limited",
        "procurementMethodDetails": "Award procedure without prior publication of a call for competition",
        "procurementMethodRationale": "The equipment to be procured must be a Crystallisation Reactor to expand our current capabilities in solvent screening and process optimisation. The system must have parallel reactors which can operate with independent temperature conditions and have a working volume of 1 - 10 mL per reactor. In-situ imaging for each reactor must be possible and fully integrated with each of the reactor conditions. A secondary indicator of particle dissolution/evolution in addition to imaging must also be available. The system must be software controlled with a highly user-friendly interface. That Technobis Crystallization Systems B.V. is the only global provider of the Crystalline, a turbidity measurement system with in-situ optics and Raman integration using small sample size. This unique technology to the market meets the following specifications: a) Ability to work with small sample volumes (2-5 mL). b) Contains 8 reactors in eight separate heating zones which can be controlled between -25 and 150 deg C. c) System is controlled by a unique software that allows easy measurements of solubility, crystallization and determination of the metastable zone width in precipitation/ crystallization processes. d) Ability to stir using overhead stirrer on small sample volumes (2-5mL) The identified system is evidenced to have a unique capability as evidenced by the following patents: 1) WO2010082817, EP2376216; Stir system and a method for providing a chemical reaction. 2) WO2007035087, EP1934587; System and method for solubility curve and metastable zone determination. The firm Technobis Crystallization Systems BV, established in Pyrietstraat 2, 1812 SC Alkmaar is the exclusive representative in the US of the products manufactured by Technobis Crystallization Systems BV, and is the only trained and competent company for the sale and support of such equipment in the United Kingdom.",
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