Award

2306/JN - Chromatography System for Protein and Nucleic Acid Purification

UNIVERSITY OF SHEFFIELD

This public procurement record has 2 releases in its history.

Award

14 Oct 2019 at 10:32

Tender

01 Aug 2019 at 10:55

Summary of the contracting process

The University of Sheffield is seeking a chromatography system for protein and nucleic acid purification through an open procurement process. The tender, titled "2306/JN - Chromatography System for Protein and Nucleic Acid Purification," falls under the goods category and is located in Sheffield, within the Yorkshire and the Humber region. The tender was published on 1st August 2019, with a closing date for submissions set for 2nd September 2019 at 12 noon UK time. The contract is valued at £65,000 and will be awarded following a competitive evaluation as part of the open procedure, which is being conducted below the threshold for EU procurement procedures.

This tender presents a significant opportunity for businesses specialising in laboratory equipment, particularly those that manufacture chromatography systems capable of various protein purification methods. Companies with expertise in affinity chromatography, anion and cation exchange, and size exclusion chromatography would be particularly well-suited to compete. Furthermore, as the equipment will serve a collaborative research group within the University, providers who can demonstrate reliability and technical capability in the life sciences sector may find this an advantageous opportunity to establish or grow their market presence.

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Notice Title

2306/JN - Chromatography System for Protein and Nucleic Acid Purification

Notice Description

The Bose Lab works on understanding the function of non-coding RNA: protein complexes, and how they regulate gene expression. The group uses a combination of functional genomics, biochemistry and structural biology to probe the mechanism of protein:RNA complexes. The lab is generously funded by a Sir Henry Dale Fellowship from the Wellcome Trust and the Royal Society. The group is also associated with a wider cross-faculty and departmental grouping of labs focused on nucleic acids research within the University of Sheffield as part of the Sheffield Institute for Nucleic Acids; the equipment will therefore be of wider interest to a number of groups within the University. Our work studies how non-protein coding RNAs (ncRNAs) interact with and regulate distinct activities in regulatory enzyme complexes that control chromatin accessibility and therefore transcription in mammalian systems. We have previously shown that direct interactions with ncRNAs are a key regulatory factor for these enzymes. The biochemical and structural biology experiments carried out in the group require the formation of diverse protein:nucleic acid complexes, and their subsequent purification to high levels of purity. We also incorporate a variety of fluorophores into our purified samples. As many of these complexes are only weakly associated or transient, accurate sample preparation requires the ability to operate a number of preparation protocols quickly and reproducibly. Importantly, the ability to simultaneously detect the presence of both protein and RNA components in the sample formation reaction would be beneficial to ensure complexes are formed prior to their use in downstream experiments. The University now requires a chromatography system to support the research into this area. In order to purify proteins, RNA and protein:RNA complexes, the system must be capable of a number of distinct protein purification applications, including but not limited to: Affinity chromatography (e.g Ni/Co affinity, GST, Strep-tag), Anion and cation exchange, and size exclusion chromatography. To preserve the activity and integrity of the purified samples, the system will be housed in a climate controlled cold cabinet operated at 4C. The ability to control and monitor the system remotely would be advantageous. This is an Non-EU open exercise. The ITT can be downloaded by registering and expressing your interest on the University's e-tendering system https://in-tendhost.co.uk/sheffield If you have any questions or comments in relation to this tender they must be submitted via the In-tend system, this can be accessed at https://in-tendhost.co.uk/sheffield Completed tenders must be returned through the same e-tendering system. Closing date for receipt of tenders: 2nd September 2019 at 12 noon (UK time).

Publication & Lifecycle

Open Contracting ID
ocds-b5fd17-19e536db-f5a4-426b-b2c7-54a1c5721a7a
Publication Source
Contracts Finder
Latest Notice
https://www.contractsfinder.service.gov.uk/Notice/e177b1c6-54df-4fa4-8cca-cd9a8463a31a
Current Stage
Award
All Stages
Tender, Award

Procurement Classification

Notice Type
Award Notice
Procurement Type
Standard
Procurement Category
Goods
Procurement Method
Open
Procurement Method Details
Open procedure (below threshold)
Tender Suitability
SME
Awardee Scale
Large

Common Procurement Vocabulary (CPV)

CPV Divisions

38 - Laboratory, optical and precision equipments (excl. glasses)


CPV Codes

38432200 - Chromatographs

Notice Value(s)

Tender Value
£65,000 Under £100K
Lots Value
Not specified
Awards Value
£65,000 Under £100K
Contracts Value
Not specified

Notice Dates

Publication Date
14 Oct 20196 years ago
Submission Deadline
2 Sep 2019Expired
Future Notice Date
Not specified
Award Date
9 Oct 20196 years ago
Contract Period
20 Oct 2019 - 22 Oct 2019 30 days
Recurrence
Not specified

Notice Status

Tender Status
Complete
Lots Status
Not Specified
Awards Status
Active
Contracts Status
Not Specified

Contracting Authority (Buyer)

Main Buyer
UNIVERSITY OF SHEFFIELD
Contact Name
Available with D3 Tenders Premium →
Contact Email
Available with D3 Tenders Premium →
Contact Phone
Available with D3 Tenders Premium →

Buyer Location

Locality
SHEFFIELD
Postcode
S10 2TN
Post Town
Sheffield
Country
England

Major Region (ITL 1)
TLE Yorkshire and The Humber
Basic Region (ITL 2)
TLE3 South Yorkshire
Small Region (ITL 3)
TLE32 Sheffield
Delivery Location
TLE Yorkshire and The Humber

Local Authority
Sheffield
Electoral Ward
Broomhill and Sharrow Vale
Westminster Constituency
Sheffield Central

Supplier Information

Number of Suppliers
1
Supplier Name

GE HEALTHCARE

Further Information

Notice Documents

Open Contracting Data Standard (OCDS)

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