Notice Information
Notice Title
Seahorse XF Pro analyser
Notice Description
The Centre for Cardiovascular Science (CVS) is part of the new Institute of Neuroscience and Cardiovascular Research (INCR). CVS comprises ~200 researchers encompassing a wide range of cardiovascular research split into four main themes (Metabolism, Obesity and Diabetes; Coronary and Valvular Heart Disease; Hypertension and Renal; Cardiometabolic Imaging). The equipment will allow high sensitivity measurement of real-time respiration in immortalised and primary cells and in tissue explants in several species.
Lot Information
Lot 1
The Centre for Cardiovascular Science (CVS) is part of the new Institute of Neuroscience and Cardiovascular Research (INCR). CVS comprises ~200 researchers encompassing a wide range of cardiovascular research split into four main themes (Metabolism, Obesity and Diabetes; Coronary and Valvular Heart Disease; Hypertension and Renal; Cardiometabolic Imaging). Centre for Cardiovascular Science (CVS) requests an Agilent Seahorse XFe24 analyser and software for high throughput real-time metabolic analysis of living cells and tissue explants. The instrument will add easy-to-use capability for metabolic measurements in living cells to better understand cellular metabolism. The replacement XFe24 machine will support the requirements of the centre to deliver world-leading research in the field of metabolism. The replacement XFe24 will allow high sensitivity measurement of real-time respiration in immortalised and primary cells and in tissue explants in several species.
Procurement Information
Seahorse XF instruments are the only ones that can simultaneously measures oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) of living cells, and do so with unrivalled speed and requiring less material, even than other systems that solely measure OCR. Using these measurements, glycolytic Proton Efflux Rate (PER) is easily calculated as an accurate measurement of glycolysis rates in real time. This measurement technology is covered by US patent # 7,276,351 meaning that no other company can offer this capability. The XFe24 Seahorse is the only commercially available instrument for scientific research that simultaneously measures the two major energy-producing pathways of the cell, mitochondrial respiration and glycolysis. The requested instrument is unique in its offerings and ability to perform measurements in living cells without using destructive methods, thus preserving cellular integrity, and allowing researchers to follow cell fate over time. The XFe24 allows simultaneous analysis of a plate containing 24 wells - and has the ability to study 3D models (e.g. islets, adipose cells and tissue explants) which is crucial for several groups in CVS. Four compounds can be injected sequentially into each of the 24 wells during measurement of cellular respiration (oxygen consumption and extracellular acidification) to determine cellular responses in real time. Unique technical features not found in any other instruments Instrument creates transient microchamber, makes optical measurements, and performs compound injections. Temperature controlled measurement chamber is maintained at 37degC +- 0.5degC; alternative temperatures supported. XFe analyzers are also supported to for analysis in a hypoxic chamber. Seahorse XF instruments are the only ones that can simultaneously measures oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) of living cells, and do so with unrivalled speed and requiring less material, even than other systems that solely measure OCR. The precision-molded enclosures on Agilent Seahorse XFe have specialty coatings and gaskets to shield the electronics and sample from ambient light, as well as block radiated and emitted electromagnetic interference
Notice Details
Publication & Lifecycle
- Open Contracting ID
- ocds-r6ebe6-0000757767
- Publication Source
- Public Contracts Scotland
- Latest Notice
- https://www.publiccontractsscotland.gov.uk/search/show/search_view.aspx?ID=FEB498779
- Current Stage
- Award
- All Stages
- Award
Procurement Classification
- Notice Type
- PCS Notice - Website Contract Award Notice
- Procurement Type
- Standard
- Procurement Category
- Goods
- Procurement Method
- Limited
- Procurement Method Details
- Award procedure without prior publication of a call for competition
- Tender Suitability
- Not specified
- Awardee Scale
- Large
Common Procurement Vocabulary (CPV)
- CPV Divisions
38 - Laboratory, optical and precision equipments (excl. glasses)
-
- CPV Codes
38434000 - Analysers
Notice Value(s)
- Tender Value
- Not specified
- Lots Value
- Not specified
- Awards Value
- Not specified
- Contracts Value
- £194,806 £100K-£500K
Notice Dates
- Publication Date
- 14 Feb 20242 years ago
- Submission Deadline
- Not specified
- Future Notice Date
- Not specified
- Award Date
- 8 Feb 20242 years ago
- Contract Period
- Not specified - Not specified
- Recurrence
- Not specified
Notice Status
- Tender Status
- Complete
- Lots Status
- Complete
- Awards Status
- Not Specified
- Contracts Status
- Active
Buyer & Supplier
Contracting Authority (Buyer)
- Main Buyer
- UNIVERSITY OF EDINBURGH
- Contact Name
- Andy Oughton
- Contact Email
- aoughton@ed.ac.uk
- Contact Phone
- +44 1316502508
Buyer Location
- Locality
- EDINBURGH
- Postcode
- EH1 1HT
- Post Town
- Edinburgh
- Country
- Scotland
-
- Major Region (ITL 1)
- TLM Scotland
- Basic Region (ITL 2)
- TLM1 East Central Scotland
- Small Region (ITL 3)
- TLM13 City of Edinburgh
- Delivery Location
- TLM75 City of Edinburgh
-
- Local Authority
- City of Edinburgh
- Electoral Ward
- City Centre
- Westminster Constituency
- Edinburgh East and Musselburgh
Further Information
Notice Documents
-
https://www.publiccontractsscotland.gov.uk/search/show/search_view.aspx?ID=FEB498779
Seahorse XF Pro analyser - The Centre for Cardiovascular Science (CVS) is part of the new Institute of Neuroscience and Cardiovascular Research (INCR). CVS comprises ~200 researchers encompassing a wide range of cardiovascular research split into four main themes (Metabolism, Obesity and Diabetes; Coronary and Valvular Heart Disease; Hypertension and Renal; Cardiometabolic Imaging). The equipment will allow high sensitivity measurement of real-time respiration in immortalised and primary cells and in tissue explants in several species.
Open Contracting Data Standard (OCDS)
View full OCDS Record for this contracting process
The Open Contracting Data Standard (OCDS) is a framework designed to increase transparency and access to public procurement data in the public sector. It is widely used by governments and organisations worldwide to report on procurement processes and contracts.
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